Infectious diseases. Herpes simplex clinic (most important)

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Infectious diseases. Herpes simplex clinic (most important)

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43. Herpes simplex clinic

The incubation period is 2-14 days, on average - 6. Clinical manifestations depend on the location of the lesion and its prevalence.

1. Damage to the mucous membranes and skin. On the skin, the changes look like conglomerates of thin-walled vesicles with an erythematous base, they rupture, crust and heal in 7-10 days.

2. Traumatic skin injuries predispose to the development of herpetic eruptions. In this case, the primary infection is more often manifested by single vesicles, and the recurrent one - by their clusters, the vesicles appear at the site of infection after 2-3 days.

3. Acute herpetic gingivostomatitis. In children aged 1-3 years, the primary infection is manifested by stomatitis. Symptoms develop acutely, pain in the mouth, salivation, bad breath appear, the child refuses to eat, his body temperature rises to 40-40,6 ° C. Vesicles form on the mucous membrane, which quickly burst, ulcers 2-10 mm in diameter are formed, covered with a grayish-yellow film.

4. Recurrent stomatitis is characterized by isolated changes localized in the soft palate or near the lips and accompanied by fever.

5. Massive infection with the herpes virus of the altered eczematous skin is accompanied by the development of herpetic eczema. In typical cases, numerous vesicles appear at the site of eczematous changes. New rashes may appear within 7-9 days. At first they are isolated, but then they are grouped and directly adjacent to the healthy skin area. The epithelium may slough off. Healing usually occurs with scar formation.

6. Infection of the eyes. Primary infection with the herpes virus and its relapses are manifested by conjunctivitis and keratoconjunctivitis. In a primary infection, the parotid lymph nodes enlarge and thicken.

7. Herpes in the vulva is most common in adolescents and young adults through sexual contact and is usually caused by HVH-2. If the patient does not have antibodies to the herpes virus, then he develops general disorders

8. Systemic infection. Newborns in most cases become infected during childbirth when passing through the birth canal infected with the HVH-2 virus, or when the fetal bladder ruptures.

Clinical manifestations develop during the first 2 weeks and consist in characteristic skin lesions, lethargy, the child does not take the breast well, persistent acidosis, liver enlargement, pneumonitis, meningoencephalitis are noted.

9. Meningoencephalitis. In newborns, it is usually caused by HVH-2, and in older age groups by HVH-1. Its pathogenesis remains unknown, but it can develop even in immune individuals in whose blood antibodies circulate.

Author: Pavlova N.V.

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