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English for doctors. Hematopoietic tissue. Erythropoiesis (most important) Directory / Lecture notes, cheat sheets Table of contents (expand) 21. Hematopoietic tissue. Erythropoiesis Hematopoietic tissue is composed of reticular fibers and cells, blood vessels, and sinusoids (thin-walled blood channels). Myeloid, or blood cell-forming tissue, is found in the bone marrow and provides the stem cells that develop into erythrocytes, granulocytes, agranulocytes, and platelets. Red marrow is characterized by active hematopoiesis; yellow bone marrow is inactive and contains mostly fat cells. In the human adult, hematopoiesis takes place in the mar row of the flat bones of the skull, ribs and sternum, the vertebral column, the pelvis, and the proximal ends of some long bones. Erythropoiesis is the process of RBC formation. Bone marrow stem cells (colony-forming units, CFUs) differentiate into proerythroblasts under the influence of the glycoprotein erythropoietin, which is produced by the kidney. Proerythroblast is a large basophilic cell containing a large spherical euchromatic nucleus with prominent nucleoli. Basophilic erythroblast is a strongly basophilic cell with nucleus that comprises approximately 75% of its mass. Numerous cytoplasmic polyribosomes, condensed chro-matin, no visible nucleoli, and continued hemoglobin synthesis characteristics of this cell. Polychromatophilic erythroblast is the last cell in this line undergoes mitotic divisions. Its nucleus comprises approximately 50% of its mass and contains condensed chroma-tin which appears in a "checkerboard" pattern. The po-lychnsia of the cytoplasm is due to the increased quantity of acidophilic hemoglobin combined with the basophilia of cytoplasmic polyribosomes. Normoblast (orthochromatophilic erythroblast) is a cell with a small heterochromatic nucleus that comprises ap proximately 25% of its mass. It contains acidophilic cytoplasm because the large amount of hemoglobin and degenerating organelles. The pyknotic nucleus, which is no longer capable of division, is extruded from the cell. Reticulocyte (polychromatophilic erythrocyte) is an immature acidophilic denucleated RBC, which still contains some ribosomes and mitochondria involved in the synthesis of a small quantity of hemoglobin. Approximately 1% of the circulating RBCs are reticulocytes. Erythrocyte is the mature acidophilic and denucleated RBC. Erythrocytes remain in the circulation approximately 120 days and are then recycled by the spleen, liver, and bone marrow. new words reticular - mesh sinusoids - sinusoids granulocytes - granulocytes agranulocytes - agranulocytes active - active yellow - yellow glycoprotein - glycoprotein erythropoietin - erythropoietin amount - the amount hemoglobin - hemoglobin degenerating - degenerating condensed - compressed Author: Elena Belikova << Back: Plasma >> Forward: Hematopoietic tissue We recommend interesting articles Section Lecture notes, cheat sheets: ▪ National economy. Lecture notes ▪ Operative surgery. Lecture notes ▪ Faculty Therapy. Lecture notes See other articles Section Lecture notes, cheat sheets. Read and write useful comments on this article. Latest news of science and technology, new electronics: The existence of an entropy rule for quantum entanglement has been proven
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