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English for doctors. Plasma (most important)

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20. Plasma

Plasma is the extracellular component of blood. It is an aqueous solution containing proteins, inorganic salts, and organic com pounds. Albumin is the major plasma protein that maintains the osmotic pressure of blood. Other plasma proteins include the globulins (alpha, beta, gamma) and fibrino-gen, which is necessary for the formation of fibrin in the final step of blood coagulation. Plasma is in equilibrium with tissue interstitial fluid through capillary walls; therefore, the composition of plasma may be used to judge the mean composition of the extracellular fluids. Large blood proteins remain in the intravascular compartment and do not equilibrate with the interstitial fluid. Serum is a clear yellow fluid that is separated from the coagulum during the process of blood clot formation. It has the same com position as plasma, but lacks the clotting factors (especially fib rinogen).

Lymphatic vessels

Lymphatic vessels consist of a fine network of thin-walled vessels that drain into progressively larger and progressively thicker-walled collecting trunks. These ultimately drain, via the thoracic duct and right lymphatic duct, into the left and right subclavian veins at their angles of junction with the internal jugular veins, respectively. The lymphatics serve as a one-way (ie, towards the heart) drainage system for the return of tissue fluid and other diffusible substances, including plasma proteins, which constantly escape from the blood through capillaries. They are also important in serving as a conduit for channeling lymphocytes and antibodies produced in lymph nodes into the blood circulation.

Lymphatic capillaries consist of vessels lined with endothelial cells, which begin as blind-ended tubules or sac-cules in most tis sues of the body. Endothelium is attenuated and usually lacks a continuous basal lamina. Lymphatic vessels of large diameter resemble veins in their structure but lack a clear-cut separation between layers. Valves are more numerous in lymphatic vessels. Smooth muscle cells in the media layer engage in rhythmic contraction, pumping lymph towards the venous system. Smooth muscle is well-developed in large lymphatic ducts.

Circulation of lymph is slower than that of blood, but it is nonetheless an essential process. It has been estimated that in a single day, 50% or more of the total circulating protein leaves the blood circulation at the capillary level and is recaptured by the lymphatics.

Distribution of lymphatics is ubiquitous with some notable exceptions, including epithelium, cartilage, bone, central nervous system, and thymus.

new words

plasma - plasma

extracellular - extracellular

aqueous - water

solution - solution

proteins - proteins

inorganic - inorganic

salts - salts

organic - organic

albumin - albumin

globulins - globulins

alpha - alpha

beta - beta

gamma - gamma

fibrinogen - fibrinogen

lymphatic - lymphatic

vessel - vessel

endothelium - endothelium

circulation - blood circulation

lymph - lymph

ubiquitous - ubiquitous

notable - famous

Author: Elena Belikova

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