Obstetrics and gynecology. Hypocoagulative phase of DIC syndrome (most important)

Lecture notes, cheat sheets
Free library / Directory / Lecture notes, cheat sheets

Obstetrics and gynecology. Hypocoagulative phase of DIC syndrome (most important)

Lecture notes, cheat sheets

Table of contents (expand)

39. Hypocoagulation phase of DIC syndrome

Low shock blood pressure, as a rule, is successfully stopped by the introduction of relatively small doses of colloid solutions (up to 500 ml). If this is not done in a timely manner, then there will be a lot of tissue thromboplastin in the blood, loose platelet clots will turn into fibrin clots, which, undergoing enzymatic decay, will lead to the release of a large mass of PDPs with thrombolytic activity into the blood. With such a vicious circle, the hypocoagulable stage of the DIC syndrome unfolds. At the same time, characteristic accumulations of venous blood appear on pale skin, looking like cadaveric spots. The upper limit of blood pressure is steadily lowered, heart sounds become deaf, the ECG may decrease the height of the T wave. When auscultation of the lungs is determined in some parts of the bronchial tone of the breath. On the radiograph, cloud-like symmetrical shadows are visible - interstitial edema due to stasis of erythrocytes. Often there is a slight increase in the liver. This condition can be corrected by transfusing immediately and quickly (within 30 minutes) at least 1 L of fresh frozen plasma. The purpose of this transfusion is the rapid and high-quality replenishment of spent plasma coagulation factors, the restoration of blood fluidity. Taking into account the possibility of negative consequences of transfusion of a large amount of fresh frozen plasma, at present, already in the early stages of blood loss, a complex of a colloidal solution (preferably a hydroethyl starch solution) and crystalloids in a ratio of 1: 2 by volume, respectively, should be used instead. Their introduction in an adequate amount quickly and reliably restores hemodynamic parameters and, above all, mean arterial pressure. At the same time, the rheological properties of blood are improved, which ensures more active microcirculation in the affected tissues and organs and the restoration of increased permeability of the walls of blood vessels. If necessary, preparations containing blood coagulation factors, as well as fresh frozen plasma, can be used together with colloidal solutions.

During the hypocoagulation phase of the DIC syndrome, bleeding is systemic in nature as a result of a deficiency in the hemostasis system of plasma factors and platelets. Bleeding continues from the uterine cavity due to the fact that it has a wound surface after removal of the placenta. After the extirpation of the uterus, the stitches applied both in the abdominal cavity and on the skin bleed. It is erroneous in such circumstances to transfuse whole blood and red blood cells. In DIC syndrome, the capillaries of the pulmonary alveoli are sharply expanded, filled with accumulations of red blood cells, which leads to impaired oxygen diffusion in the lungs. Blood oxygenation is sharply reduced, and the transfusion of erythrocyte mass leads to an even greater accumulation of erythrocytes in the pulmonary capillaries and not to an improvement in oxygenation, but to its further deterioration. The puerperal at this time has a sharp pallor, not due to the loss of red blood cells, but due to the centralization of blood circulation - spasm and desolation of the vessels of the skin, mucous membranes, muscles.

Author: Ivanov A.I.

<< Back: Infusion-transfusion therapy of acute massive blood loss in obstetrics and gynecology

>> Forward: Modern technologies for providing emergency infusion-transfusion care in acute massive blood loss

We recommend interesting articles Section Lecture notes, cheat sheets:

▪ Marketing. Crib

▪ Psychology of Personality. Crib

▪ Russian literature of the XX century in brief. Crib

See other articles Section Lecture notes, cheat sheets.

Read and write useful comments on this article.

<< Back

Latest news of science and technology, new electronics:

The existence of an entropy rule for quantum entanglement has been proven 09.05.2024

Quantum mechanics continues to amaze us with its mysterious phenomena and unexpected discoveries. Recently, Bartosz Regula from the RIKEN Center for Quantum Computing and Ludovico Lamy from the University of Amsterdam presented a new discovery that concerns quantum entanglement and its relation to entropy. Quantum entanglement plays an important role in modern quantum information science and technology. However, the complexity of its structure makes understanding and managing it challenging. Regulus and Lamy's discovery shows that quantum entanglement follows an entropy rule similar to that for classical systems. This discovery opens new perspectives in the field of quantum information science and technology, deepening our understanding of quantum entanglement and its connection to thermodynamics. The results of the study indicate the possibility of reversibility of entanglement transformations, which could greatly simplify their use in various quantum technologies. Opening a new rule ... >>

Mini air conditioner Sony Reon Pocket 5 09.05.2024

Summer is a time for relaxation and travel, but often the heat can turn this time into an unbearable torment. Meet a new product from Sony - the Reon Pocket 5 mini-air conditioner, which promises to make summer more comfortable for its users. Sony has introduced a unique device - the Reon Pocket 5 mini-conditioner, which provides body cooling on hot days. With it, users can enjoy coolness anytime, anywhere by simply wearing it around their neck. This mini air conditioner is equipped with automatic adjustment of operating modes, as well as temperature and humidity sensors. Thanks to innovative technologies, Reon Pocket 5 adjusts its operation depending on the user's activity and environmental conditions. Users can easily adjust the temperature using a dedicated mobile app connected via Bluetooth. Additionally, specially designed T-shirts and shorts are available for convenience, to which a mini air conditioner can be attached. The device can oh ... >>

Energy from space for Starship 08.05.2024

Producing solar energy in space is becoming more feasible with the advent of new technologies and the development of space programs. The head of the startup Virtus Solis shared his vision of using SpaceX's Starship to create orbital power plants capable of powering the Earth. Startup Virtus Solis has unveiled an ambitious project to create orbital power plants using SpaceX's Starship. This idea could significantly change the field of solar energy production, making it more accessible and cheaper. The core of the startup's plan is to reduce the cost of launching satellites into space using Starship. This technological breakthrough is expected to make solar energy production in space more competitive with traditional energy sources. Virtual Solis plans to build large photovoltaic panels in orbit, using Starship to deliver the necessary equipment. However, one of the key challenges ... >>

Random news from the Archive

NVIDIA began to assemble some video cards on its own 26.11.2010

NVIDIA has announced certain changes to its policy.

If earlier it only provided third-party assemblers with reference models that could be used to design accelerators with a similar cooling system and other design elements, now NVIDIA intends to produce video cards on its own production lines.

Other interesting news:

▪ Ultra-strong glass harder than diamond

▪ Allergy to people

▪ Synthesized a new form of carbon

▪ Analog Devices MEMS switches instead of relays

▪ Chocolate in the morning helps women lose weight

News feed of science and technology, new electronics

Interesting materials of the Free Technical Library:

▪ section of the site Reference materials. Article selection

▪ article Burned in milk (burned in milk) - blowing on water. Popular expression

▪ article How does a snake manage to swallow a pig? Detailed answer

▪ article Forester forestry. Job description

▪ article Finding faulty elements with a thermometer. Encyclopedia of radio electronics and electrical engineering

▪ article Satellite TV signal splitters. Encyclopedia of radio electronics and electrical engineering

Leave your comment on this article:

All languages of this page

Home page | Library | Articles | Website map | Site Reviews