Lecture notes, cheat sheets
Internal illnesses. Chronic bronchitis (lecture notes) Directory / Lecture notes, cheat sheets Table of contents (expand) LECTURE No. 23. Chronic bronchitis Chronic bronchitis is a diffuse inflammatory and degenerative process in the bronchial mucosa and peribronchial tissue, manifested by persistent or recurrent cough with sputum for at least 3 months a year for 2 years or more. Etiology. The causative factors are smoking (in smokers, the incidence of chronic bronchitis is 2-5 times higher), infection (viral or bacterial), toxic effects, occupational hazards, α-1-antitrypsin deficiency, household air pollution (combustion products of fossil fuels, food odors). heating devices). Pathogenesis. There is hyperplasia of the goblet cells of the bronchial glands, hypersecretion of mucus in the bronchi and a change in its properties, inflammatory edema and infiltration of the bronchial mucosa, impaired bronchial patency and drainage function of the bronchi, an imbalance between proteinase inhibitors (α-1-antitrypsin) and proteinases (neutrophil elastase). Classification. Chronic bronchitis is divided into simple, mucopurulent and mixed. Depending on the characteristics of the clinical course, all forms of chronic bronchitis are differentiated according to the severity of the course, the phase of the disease (exacerbation, remission), as well as complications. Clinic. When simple chronic bronchitis there is a cough (at first dry in the morning, then with a small amount of mucopurulent sputum up to 20 ml / day), malaise, weakness, fatigue, auscultatory: hard breathing, sometimes weakened; with mucopurulent chronic bronchitis, moist, sonorous fine bubbling rales may occur). RџSЂRё chronic obstructive bronchitis there is an increase in cough, sputum, shortness of breath, diffuse cyanosis (lips, earlobes, acrocyanosis), rare deep breathing, barrel-shaped chest, percussion: displacement of the borders of the lungs down, their inactivity, box sound. Auscultatory listens to evenly weakened breathing with prolonged expiration, scattered dry buzzing rales, disappearing after coughing. There are 2 variants of the disease: emphysematous (associated with panacytic emphysema) and bronchitis (associated with centriacinar emphysema). Additional diagnostic study. A general blood test is carried out, where leukocytosis is detected, an increase in ESR in simple and mucopurulent bronchitis during exacerbations, hematocrit in obstructive bronchitis in men is more than 52%, in women more than 47%. An immunological blood test is also carried out (a decrease in the activity of nonspecific and humoral parts of the immune response, an increase in the activity of a cellular link in obstructive bronchitis), a sputum examination (macro- and micro-study - cytology, flora), a calculation of the index of a smoking person (the number of cigarettes smoked per day, multiplied by 12 (number of months in a year); with a value of 160 there is a risk for chronic obstructive bronchitis, more than 200 - classification as "heavy smokers"). The functional state of the lungs is examined (determination of volumetric and speed indicators) - peak flow measurements, spirography, pneumotachometry are used. OVF1 is monitored (long-term re-measurement of the spirometric index): normally, in adulthood, there is an annual drop in OVF1 within 30 ml per year; for patients with chronic obstructive bronchitis, an annual drop in the GFR1 index of more than 50 ml per year is typical. Conduct a bronchological examination (hyperemia, edema, atrophy of the mucosa, the presence of sputum, dyskinesia of the bronchus wall), computed tomography (morphological changes in the lungs, their location, size), ECG (exclusion of cardiac genesis of symptoms, determination of hypertrophy of the right heart - rightogram, deep prong S in V5, V6). Complications. Complications of the disease can be focal pneumonia, emphysema, respiratory failure, chronic cor pulmonale, secondary erythrocytosis, bronchiectasis; Differential diagnostics. Should be carried out with chronic pneumonia, tuberculosis, lung cancer, bronchial asthma. Treatment. Treatment is carried out in the phase of exacerbation and the phase of remission. В exacerbation phase antibacterial therapy is carried out (in the presence of purulent sputum), M-cholinolytics are prescribed, β2-agonists, methylxanthines, mucolytics, antihistamines, oxygen therapy, therapeutic bronchoscopy, physiotherapy, exercise therapy, treatment of complications. В remission phase patients are prescribed bronchodilators (if indicated), mucolytics (used for symptoms of mucostasis), physiotherapy, spa treatment. Flow. The course of the disease can be recurrent, chronic, progressive. Prevention. Prevention measures include the following: timely treatment of acute bronchitis and respiratory diseases, early detection and treatment of the initial stages of chronic bronchitis, hardening of the body (air and sun baths, water procedures), measures to combat dust and air pollution in working areas, smoking restriction, sanitation foci of chronic infection. Author: Myshkina A.A. << Back: pneumonia >> Forward: Bronchiectasis We recommend interesting articles Section Lecture notes, cheat sheets: ▪ General psychology. Lecture notes ▪ infectious diseases. Lecture notes See other articles Section Lecture notes, cheat sheets. Read and write useful comments on this article. Latest news of science and technology, new electronics: The existence of an entropy rule for quantum entanglement has been proven
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