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Internal illnesses. Bronchiectasis (lecture notes) Directory / Lecture notes, cheat sheets Table of contents (expand) LECTURE No. 24. Bronchiectasis Regional expansion of the bronchi with a predominant localization of the process in the lower parts of the lungs, manifested by chronic endobronchial suppuration. The disease is associated with genetic defects in the development of the bronchi, observed in children and adults. Men get sick more often. Secondary bronchiectasis, in which damage to the lung tissue predominates due to an active inflammatory process, does not belong to bronchiectasis. Etiology. Etiological factors include bronchopulmonary infections, aspiration of foreign bodies, bronchial stenosis with secretion retention and constant suppuration distal to the stenosis, bronchial malformations, congenital predisposition (Sievert-Kartagener syndrome). Pathogenesis. Bronchial patency is disturbed (formation of obstructive atelectasis), inflammation of the bronchi occurs, intrabronchial pressure increases, elasticity and mechanical stability of the bronchi decreases, obturation of small bronchi occurs (cystic fibrosis). Classification. According to the features of clinical manifestations, the disease is divided: 1) according to the form of bronchiectasis (saccular, fusiform, cylindrical, mixed); 2) according to the phase of the disease (exacerbation, remission); 3) by localization (segment, segments, right- or left-sided). Clinic. The main manifestations of the disease are: productive cough, mainly in the morning, with the separation of a significant amount of mucopurulent or purulent sputum, hemoptysis, sputum separation depends on the position of the body - it increases in a state of orthopnea. Patients note intoxication, weight loss, fever, puffiness of the face, earthy shade of diffuse cyanosis, retraction of the affected side of the chest. Fingers in the form of drumsticks, nails in the form of watch glasses (a sign of hypoxia). During percussion, a mosaic of percussion sound is determined (a sign of low specificity). Harsh breathing, foci of persistent moist medium and coarse bubbling rales, loud dry rales are auscultated. Additional diagnostic study. A general blood test is performed, in which anemia, neutrophilic leukocytosis with a shift to the left, and an increase in ESR are noted. Also, a study of a general urine test is carried out (with the development of complications - the appearance of a protein), a biochemical blood test (dysproteinemia: hypoproteinemia, albuminemia, hypergammaglobulinemia), a sputum examination (macro- and microscopic examination of the flora: three-layer, many leukocytes). With bronchoscopy, a lot of sputum is found in the lumen of the bronchi, there is hyperemia of the mucosa, a continuous flow of sputum. With bronchography - bronchiectasis of various forms, with radiography - a decrease in the volume of the affected lung, cellularity of the pulmonary pattern. A functional study of the lungs is being carried out. Complications. Complications of the disease are pulmonary bleeding, pleural empyema, pyopneumothorax, lung abscesses, amyloidosis of internal organs, cor pulmonale. Differential diagnosis. Should be carried out with chronic pneumonia, tuberculosis, chronic lung abscess, lung cancer. Treatment. Patients are shown diet No. 15, active positional drainage according to B. E. Votchal. Antibacterial drugs (parenteral and intrabronchial), repeated sanitation bronchoscopy, bronchodilator therapy, mucolytics, desensitizing agents, anabolic hormones, vitamins (groups B, C) are prescribed; surgical treatment (segmental resection, lobectomy) is indicated for one lobe. Flow. The course of the disease is progressive, long-term remissions are possible. Forecast. With a limited lesion, the prognosis is favorable, and with a widespread process and the presence of complications, it is unfavorable. Prevention. Prevention measures include timely treatment of lung infections, smoking cessation, systematic positional drainage, and treatment of complications. Author: Myshkina A.A. << Back: Chronical bronchitis >> Forward: lung abscess We recommend interesting articles Section Lecture notes, cheat sheets: ▪ International economic relations. Crib See other articles Section Lecture notes, cheat sheets. Read and write useful comments on this article. Latest news of science and technology, new electronics: The existence of an entropy rule for quantum entanglement has been proven
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