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Histology. Epithelial tissue

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Topic 9. EPITHELIAL TISSUES

Characterization of epithelial tissues

They form the outer and inner layers of the body.

Functions of the epithelium:

1) protective (barrier);

2) secretory;

3) excretory;

4) suction.

Structural and functional features of epithelial tissues:

1) arrangement of cells in layers;

2) location of cells on the basement membrane;

3) the predominance of cells over the intercellular substance;

4) polar differentiation of cells (to the basal and apical poles);

5) absence of blood and lymphatic vessels;

6) high ability of cells to regenerate.

Structural components of epithelial tissue:

1) epithelial cells (epithelial cells);

2) basement membrane.

Epitheliocytes are the main structural elements of epithelial tissues.

The basement membrane (about 1 µm thick) consists of:

1) thin collagen fibrils (from collagen protein of the fourth type);

2) an amorphous substance (matrix) consisting of a carbohydrate-protein-lipid complex.

Basement membrane functions:

1) barrier (separation of the epithelium from the connective tissue);

2) trophic (diffusion of nutrients and metabolic products from the underlying connective tissue and back);

3) organizing (attachment of epitheliocytes with the help of hemidesmosomes).

Classification of epithelial tissues

There are the following types of epithelium:

1) integumentary epithelium;

2) glandular epithelium.

Genetic classification of epithelia (according to N. G. Khlopin):

1) epidermal type (develops from the ectoderm);

2) enterodermal type (develops from the endoderm);

3) whole nephrodermal type (develops from the mesoderm);

4) ependymoglial type (develops from neuroectoderm);

5) angiodermal type (or vascular endothelium developing from the mesenchyme).

Topographic classification of the epithelium:

1) skin type (skin epidermis);

2) gastrointestinal;

3) renal;

4) hepatic;

5) respiratory;

6) vascular (vascular endothelium);

7) epithelium of serous cavities (peritoneum, pleura, pericardium).

The glandular epithelium forms most of the body's glands. Consists of glandular cells (glandulocytes) and basement membrane.

Gland classification

By number of cells:

1) unicellular (goblet gland);

2) multicellular (the vast majority of glands).

According to the location of cells in the epithelial layer:

1) endoepithelial (goblet gland);

2) exoepithelial.

By the method of removing the secret from the gland and by structure:

1) exocrine glands (have an excretory duct);

2) endocrine glands (do not have excretory ducts and secrete (hormones) into the blood or lymph).

According to the method of secretion from the glandular cell:

1) merocrine;

2) apocrine;

3) holocrine.

According to the composition of the allocated secret:

1) protein (serous);

2) mucous membranes;

3) mixed (protein-mucous);

4) sebaceous.

By structure:

1) are simple;

2) complex;

3) branched;

4) unbranched.

Phases of the secretory cycle of glandular cells

There are the following phases of the secretory cycle of glandular cells:

1) absorption of the initial products of secretion;

2) synthesis and accumulation of the secret;

3) secretion (according to the merocrine or apocrine type);

4) restoration of the glandular cell.

Authors: Selezneva T.D., Mishin A.S., Barsukov V.Yu.

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