There are lees to every wine. Meaning, origin, examples of the use of phraseological units

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WINGED WORDS, PHRASEOLOGICAL UNITS
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Winged words, phraseological units. Meaning, history of origin, examples of use

Winged words, phraseological units

Directory / Winged words, phraseological units

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There are lees to every wine

Kheraskov M.M.

Phraseologism: There are lees to every wine.

Meaning: And the most worthy people have their shortcomings, no one is impeccable and cannot be impeccable (jokingly ironic).

Origin: The primary source is the poem "Rossiyada" by Mikhail Matveyevich Kheraskov (1733-1807): "There are dark places both in the sun and in the moon!"

Random phraseology:

Mind immature, the fruit of short-lived science!

Meaning:

About the lack of education (self-ironic)

Origin:

From the beginning of the first satire "On those who blaspheme the teachings. To their own mind" (1729) by the Russian poet Antioch Dmitrievich Kantemir (1708-1744), which until its first publication (1762) went only in the lists: "Unripe mind, the fruit of a short science! // Rest in peace, do not force my hands to write a pen ... "

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Microwaves for drugs 11.06.2013

It turns out that microwave radiation, familiar to us from home microwave ovens and used to heat food, can be useful for the pharmaceutical industry. Researchers from the University of Bradford (UK) have found that the use of microwaves can provide a fast and environmentally friendly way to produce medicines.

Microwave radiation, as first proven by scientists in the UK, can be effectively used for co-crystallization, a process that creates single crystals built from two compounds. Drugs obtained in this way can outperform their competitors in terms of shelf life, water solubility and, importantly, absorption into the blood, that is, fewer doses will be needed to achieve the desired effect.

As an example, scientists used caffeine and maleic acid. These substances were not taken by chance - they have different degrees of solubility, and this often creates problems in the manufacture of drugs, forcing the use of a large amount of not always safe solvents.

During an experiment using microwaves, the researchers were able to achieve 100% crystallization in just one minute. At the same time, as a special achievement, it is noted that the amount of solvents used was minimal, which is safe for the environment, in contrast to traditional methods for the production of pharmaceutical products.

Best of all during the experiment, such solvents as water and methanol showed themselves - they transfer heat from microwave radiation most efficiently, and acetone, ethyl acetate and toluene did not show themselves in the best way.

So far, the experiment on cocrystallization using microwaves has been carried out only in laboratory conditions, but the curators of the study are confident that the procedure can be repeated on an industrial scale and completely change the pharmaceutical production process. It is microwave radiation that should be considered as one of the promising ways to create cocrystals with minimal use of unsafe solvents.

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