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Hospital pediatrics. Vegetative-vascular dystonia. Arterial hypertension. Clinic, diagnosis, treatment (lecture notes)

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LECTURE No. 2. Vegetative-vascular dystonia. Arterial hypertension. Clinic, diagnosis, treatment

1. Vegetative-vascular dystonia

The sympathetic division of the autonomic nervous system primarily regulates adaptation and trophic processes in situations requiring intense mental and physical activity. The parasympathetic department of the autonomic nervous system exhibits its main function outside the period of intense activity of the body, mainly during the period of “rest”, and regulates anabolic processes, the insular apparatus, digestive functions, emptying of hollow organs, and helps maintain the constancy of homeostasis. Autonomic reactivity is changes in autonomic reactions to internal and external stimuli. Irritants can be pharmacological drugs (mezaton, adrenaline, etc.), as well as physical influences (cold, heat, pressure on reflexogenic zones, etc.). There are 3 types of vegetative reactivity:

1) normal (sympathicotonic);

2) hypersympathicotonic;

3) sympathicotonic.

Autonomic support is the maintenance of an optimal level of functioning of the autonomic nervous system, ensuring adequate functioning of various organs and systems under stress conditions. Vegetative support in practical work is assessed using the clinoorthostatic test (COT). Autonomic-vascular dysfunction is caused by a violation of the neurohumoral regulation of autonomic functions, which most often can appear with neuroses, physical inactivity, endocrine pathology in the prepubertal period and during menopause. But depending on the etiology and manifestations of VSD, pathogenetic disorders are distinguished at any level: cortical, hypothalamic, with a predominance of the parasympathetic division of the autonomic nervous system or the sympathetic division of the autonomic nervous system.

Determination of the variant of vegetative dystonia depending on the results of assessing the initial vegetative tone and COP. Clinical manifestations in some patients include fatigue, irritability, sleep disturbances, decreased pain sensitivity with various senestopathies. Signs of autonomic dysfunction may include palpitations with a tendency to sinus bradycardia or tachycardia; supraventricular extrasystole, paroxysmal tachycardia. Pathological vasomotor reactions can be manifested by a feeling of hot flashes, cold, decreased or increased blood pressure, pallor of the skin or hyperemia of the skin, general or local sweating, impaired secretory function, motor dysfunction of the gastrointestinal tract, and impaired sexual function. In the presence of neurovegetative imbalance, the activity of the parasympathetic nerves predominates, which is expressed by bradycardia, hyperemia of the skin, increased peristalsis of the stomach and intestines, a positive symptom of persistent red dermographism, and a decrease in pulse.

Treatment. Principles of treatment of vegetative dystonia.

1. Pathogenetic therapy, symptomatic therapy.

2. Long-term treatment to restore balance between parts of the autonomic nervous system; this requires more time than the formation of an imbalance between them.

3. An integrated approach, including various types of effects on the body.

4. Selectivity of therapy depending on the type of vegetative dystonia, both in constant (permanent) and crisis (paroxysmal) course.

The main sedatives in the treatment of vegetative dystopia in children.

1. Herbal products (valerian, motherwort, St. John's wort, viburnum, mint, oregano, sweet clover, lemon balm).

2. Tranquilizers (seduxen, tazepam, elenium, meproman).

3. Antipsychotics (sanopax, teralen, frenolon).

Non-drug therapy includes: proper organization of work and rest; maintaining a daily routine; physical education classes; balanced diet; psychotherapy; hydrotherapy and balneotherapy; physiotherapy; massage; acupuncture (according to indications). Types of sports for vegetative dystonia in children (recreational swimming, cycling, race walking, skiing, skating). Hydrotherapy depending on the type of vegetative dystonia, physiotherapy. Gymnastics, jumping, tennis, boxing, and weightlifting are not recommended. For vagotonia, showers (circular, contrast, needle, jet, Charcot shower), baths (oxygen, pearl, salt-pine) are recommended. For sympathicotonia, showers (fine, rain, circular) and baths (coniferous, sage-green) are recommended.

Stimulating and tonic herbal products (ginseng, lemongrass, eleutherococcus, green tea, licorice root). Nootropic drugs used in the complex treatment of autonomic disorders in children (piracetam, pyriditol, aminalon, glycine, glutamic acid, acepheren).

2. Arterial hypertension

Arterial hypertension is an increase in blood pressure from the mouth of the aorta to the arterioles inclusive.

Classifications of arterial hypertension: primary arterial hypertension and secondary arterial hypertension.

Etiology, pathogenesis. Etiopathogenesis of arterial hypertension.

1. Etiological factors: psycho-emotional effects, brain hypoxia, age-related neuroendocrine changes, perinatal disorders, salt overload.

2. First-line predisposing factors: hyperreactivity of nerve centers regulating blood pressure; dysfunction of norepinephrine deposympathetic structures. Borderline arterial hypertension develops.

3. Second-line predisposing factors: weakening of hypertensive renal function, disturbances of the renin-angiotensin-2-aldosterone pressor system, changes in cell membranes.

The development of hypertension in various forms

Before prepubertal age, an increase in blood pressure is observed more often with kidney diseases, endocrine pathology, coarctation of the aorta, pheochromocytoma, etc.

Classification. Classification of blood pressure levels and severity of arterial hypertension

1st degree. Systolic - 140-159 mm Hg. Art., diastolic - 90-99 mm Hg. Art.

Borderline degree: systolic - 140-149 mm Hg. Art., diastolic - 90-94 mm Hg. Art.

2st degree. Systolic - 160-179 mm Hg. Art., diastolic - 100-109 mm Hg. Art.

3rd degree. Systolic - more than 180 mm Hg. Art., diastolic - more than 110 mm Hg. Art.

Classification according to M. Ya. Studennikov.

1. Vascular vegetative dystonia of the hypertonic type.

2. Hypertension.

3. Symptomatic (secondary) hypertension.

Clinical manifestations. Often detected by chance, with diseases of the urinary system, the numbers of both maximum and minimum pressure usually increase. Hypertension with coarctation of the aorta is diagnosed by low pressure in the lower extremities and the presence of systolic murmur. Pheochromocytoma is characterized by high blood pressure crises and painful headaches; the diagnosis is established when an increased content of catecholamines is detected in the urine and blood. In prepubertal and pubertal age, hypertensive conditions occur with vegetative-vascular dystonia. Hypertension is unstable, pressure fluctuates throughout the day, and a close connection with emotional factors can be noted. There are complaints of poor health, irritability, easy fatigue, pain in the heart, feeling of heat, etc. An objective examination revealed tachycardia, inadequate response to physical activity, and autonomic lability.

Treatment. Treatment of arterial hypertension in vegetative-vascular dystonia: sedative therapy is indicated - bromine with valerian, seduxen, normalization of the daily routine, mandatory stay in the fresh air, children are shown moderate physical activity and sports with gradually increasing loads. For arterial hypertension, according to indications, diuretics, ACE inhibitors, β2-blockers, L-blockers, adrenergic blockers, and calcium channel blockers can be used.

Prevention: correct daily routine, nutrition, exercise and sports, sufficiently long sleep.

Author: Pavlova N.V.

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