Reevaluate your values. Meaning, origin, examples of the use of phraseological units

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Winged words, phraseological units. Meaning, history of origin, examples of use

Winged words, phraseological units

Directory / Winged words, phraseological units

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Reevaluate your values

Socrates

Phraseologism: Reevaluate your values.

Meaning: Take nothing for granted, check everything, judge everything for yourself.

Origin: The future great philosopher Diogenes of Sinope (400-325 BC) received such an answer from the Delphic oracle when he asked him what he should do. Following literally the advice of this soothsayer (“overestimate values”), Diogenes even became a counterfeiter. And only after meeting one of the students of Socrates, he understood the meaning of the prediction: his true vocation is to be a philosopher, to overestimate spiritual values, to make his own judgment about everything, and not to follow the established opinion.

Random phraseology:

I have very serious disagreements with the Soviet government.

Meaning:

About views that run counter to the official ideology.

Origin:

From the novel (ch. 2) "The Golden Calf" (1931) by Soviet writers Ilya Ilf (1897-1937) and Evgeny Petrov (1903-1942). Ostap Bender: "I have serious disagreements with the Soviet authorities. They want to build socialism, but I don't."

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Metabolic weight gain switch 04.09.2015

Researchers at MIT and Harvard Medical School have discovered a new way to control human metabolism and tell adipocytes, or fat cells, when to store and when to burn fat.

Scientists have found that it's all about the IRX3 and IRX5 genes, which control the process of thermogenesis, in which fats decompose and heat is produced. Usually, the process of thermogenesis is activated by exercise, diet, or sub-zero temperatures, but in some cases, its activation is very difficult.

Studies show that a single nucleotide genetic difference can lead to obesity or overweight. In individuals at risk, the nucleotide base replaces thymine with cytosine, which triggers the action of IRX3 and IRX5. Those, in turn, turn off the process of thermogenesis, which leads to the accumulation of lipids and, over time, to obesity.

By altering this nucleotide using the CRISPR/Cas9 system, a technology that allows precise changes to the DNA sequence, scientists can replace cytosine with thymine and thus turn off IRX3 and IRX5, restore thermogenesis to a safe level, and reduce lipid accumulation.

Suppressing the actions of the IRX3 gene in mice resulted in significant changes in the body's energy balance, reduction in weight and all major fat stores, and resistance to high-fat diets.

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