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ENCYCLOPEDIA OF RADIO ELECTRONICS AND ELECTRICAL ENGINEERING
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Microwave oscilloscope detector. Encyclopedia of radio electronics and electrical engineering

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Encyclopedia of radio electronics and electrical engineering / Measuring technology

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I did not intend to draw this simple detector. But the mass of letters with questions about setting up my MMDS converters showed that even novice radio amateurs are trying to repeat them. I would not advise beginners in radio engineering to take on microwave devices. Experienced radio amateurs always have at hand similar homemade "chips" like this detector. Here for those who still do not have such a prefix, this publication.

I made this sampler to set up the v.h. paths of their satellite receivers and used in conjunction with a swept frequency generator. It turned out that it is convenient to use it not only for microwaves, but also for other radio devices, even for those for which I had factory measuring instruments. And for the next 15 years, I used it constantly.

The basis of the probe is a microwave diode from direction finders or radar installations. In old military equipment, it was often used. Putting a PVC tube on it, I wrapped it with a copper tape with a grounding tail and soldered the KM-4a isolation capacitor and resistor directly to the thin terminal of the diode. The conclusion of this capacitor concerned the circuit under study. The second output of the diode and the resulting cylinder of the copper screen were completed with springy contacts. This nozzle was put on the coaxial head of the oscilloscope probe. Then I made such detectors with different diodes as independent oscilloscope probes.

Why do you need an oscilloscope? It turned out that the use of an oscilloscope as an indicator of rectified direct current has many advantages. Firstly, the oscilloscope has a high-resistance input (usually 1 MΩ) and the resulting probe loads the circuit being measured a little. In addition, the high-resistance load of the detector ensures its linearity, which makes it possible to measure very small voltages (millivolts).

microwave oscilloscope detector

The high sensitivity of the oscilloscope and the dynamic display of the envelope of the measured signal make it possible to use the probe to compare frequencies by beating on the harmonics of a radio frequency generator (GSS), to observe the processes of self-excitation of circuits, large noises and, in general, the signal in dynamics. The detector diode is designed for operating wavelengths of ~3 cm (10 GHz), so the detector is fairly linear over a wide frequency band. And although this is only an indicator, it can also accurately measure the voltage or gain of devices using the substitution method. Direct measurement on the oscilloscope scales gives only an approximate estimate of the signal level. When using the detector, do not apply more than 1 volt to it, otherwise the diode will be damaged.

To tune more powerful devices, make another probe with a higher voltage diode suitable for your purpose. In the detector, I used diodes D405A, D405B, D605, D602, KD514A, D18. The last two are at frequencies below 1 GHz. Also, the range of permissible input voltages can be expanded by using a capacitive voltage divider at the input of the detector. The length of the leads for connecting to the circuit should be as short as possible, normally 1-2 cm. The ground lead is made in the form of a 10 mm wide bar, and when measuring it must be connected first.

microwave oscilloscope detector

The measuring probe is driven into the insulating washer and we fix it in the body by punching in a circle. Mechanical loads on the capacitor C1 must be excluded so as not to damage its lining. In this probe, the output signal has a negative polarity. To reverse the display polarity, either reverse the diode or use the oscilloscope's inverted input. All parts and the body of the detector itself are assembled by soldering with low-melting solder. This is especially important for the diode.

Author: 73! UO5OHX ex RO5OWG; Publication: shustikov.by.ru

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Neurons change their own DNA 06.05.2015

The stability of DNA is the key to a long and happy life, so the cell tries to eliminate all mutations with the help of special molecular machines. Of course, here we can recall the phenomenon of crossing over, which occurs, for example, during the maturation of germ cells (and in dividing cells in general) - during crossing over, a large-scale exchange of DNA fragments occurs between homologous chromosomes.

However, this process is under careful control, and it is still tied to cell division. As for the other cases of genome instability, they arise either due to external causes (such as mutagenic radiation), or due to the not very precise work of molecular machines involved in DNA duplication and repair. A normal, healthy cell tries as closely as possible to monitor changes in chromosomes and, if possible, restore everything as it was.

All the more surprising are the results of Hongjun Song's research group at Johns Hopkins University. He and his collaborators found that normal, mature brain neurons are constantly making changes to their own DNA using epigenetic marks. As you know, in order to change the activity of a particular gene, the cell does not need to interfere with the nucleotide sequence, it is enough to supply the gene with special markers that will make it less attractive to proteins synthesizing RNA. These markers are methyl groups that are attached to the nitrogenous base of cytosine, one of the four "letters" of the genetic code. (In parentheses, just in case, we note that methyl marks and epigenetic regulation in general are far from the only way to control gene activity.)

DNA methylation is easy, but it happens that the label needs to be removed from cytosine. This is no longer so easy to do, and here a whole chain of reactions is launched, and along the way, the labeled "letter" is cut out and ordinary, unmethylated cytosine is inserted in its place. That is, a hole is formed in one of the DNA chains, which is a strong element of instability - after all, some other “letter” can mistakenly get here, and we will get a real mutation. Nevertheless, the processes of DNA methylation and demethylation are quite active in mammalian cells, even in such a “delicate” organ as the brain, which is generally protected to the maximum from an unpredictable external environment and from the rest of the body.

In their article in Nature Neuroscience, the authors write that in mouse brain neurons, demethylation activity was clearly associated with synaptic cell plasticity. Synaptic plasticity is understood as the ability of a neuron to regulate the strength of the interneuronal connection with its neighbors - thanks to it, the impulse in the chain can weaken or increase. At the molecular level, this can be seen by how the number of neurotransmitters that transmit a signal from one neuron to another changes, and how the number of neurotransmitter receptors at the "receiving side" changes - the wider the range of changes, the greater the plasticity of the neuron. So, when the Tet3 gene, which suppresses demethylation, was turned off in brain cells, synaptic plasticity increased; conversely, when Tet3 activity was stimulated, plasticity decreased.

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Synaptic plasticity is associated with the ability to learn - it is believed that the more it is, the better for the brain. But it obviously must have some kind of regulators, one of which unexpectedly turned out to be the Tet3 gene, which reacts to changes in the activity of interneuronal contacts. Of course, the question arises of how exactly this "microsurgery" of DNA, that is, the constant cutting out of letters from a sequence of nucleotides, affects the ability of synapses to respond to different signals. It is possible that the gaps in the DNA chains fall precisely on those genes that directly affect the strength and sensitivity of synapses, but what exactly happens there can only be known from further research.

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