CULTURAL AND WILD PLANTS
Cinchona reddish (reddish cinchona). Legends, myths, symbolism, description, cultivation, methods of application Directory / Cultivated and wild plants Content
Cinchona reddish (reddish cinchona), Cinchona succirubra. Photos of the plant, basic scientific information, legends, myths, symbolism
Basic scientific information, legends, myths, symbolism Sort by: Cinchona (Cinchona) Family: Malpighiaceae (Malpighiaceae) Origin: South America (Andes) Area: South America (Ecuador, Colombia, Peru, Bolivia) Chemical composition: The main active substance of the plant is quinine. Quinidine, kinidine and other alkaloids are also present. Economic value: The cinchona tree is used medicinally to treat malaria. The plant is also used in the production of soft drinks, candy, chewing gum and other products. Cinchona wood is valued for its decorative properties and is popular in carpentry. Legends, myths, symbolism: According to legend, in 1638 the wife of a Peruvian viceroy contracted malaria, and local Indians recommended that she use cinchona bark to cure her. She was cured and recommended the medicine to European physicians, who were initially skeptical but later confirmed its effectiveness. According to another legend, the name "cinchona" comes from the name of the wife of the governor of Lima, who was cured with cinchona bark in the 1630s. In Inca mythology, the cinchona tree was considered a sacred plant and was used to treat various diseases. The cinchona reddish tree is associated with the struggle for health and life. Its use to treat malaria was a revolutionary discovery in medicine and saved many lives. In South American culture, cinchona is considered a symbol of life and prosperity. Its medicinal properties have helped save the lives of many people and have also led to the development of medicine and science in the region.
Cinchona reddish (reddish cinchona), Cinchona succirubra. Description, illustrations of the plant Cinchona reddish (reddish cinchona), Cinchona succirubra pavon. Botanical description, habitat and habitats, chemical composition, use in medicine and industry An evergreen tree with a grayish-brown bark, 15-20 m high, of the madder family (Rubiaceae). Leaves opposite, wrinkled, broadly elliptical, up to 50 cm long. The flowers are pink, in false umbrellas, collected at the ends of the branches in wide-pyramidal panicles. The fruit is a two-celled, brown-brown box. 2,5-3 cm long. Seeds are flat, 4-10 mm long, light brown. Range and habitats. The natural thickets of the cinchona tree are small. The cinchona tree is cultivated in many countries of Indonesia, India, Sri Lanka. It also uses other types. Chemical composition. Dried bark of trunks, branches and roots (lat. Cortex Chinae) is used as a medicinal raw material, the main active ingredients of which are alkaloids, quinoline derivatives, including quinine and its stereoisomer quinidine and their 6-dimethoxy derivatives - cinchonine and cinchonidine. In medicine, quinine hydrochloride, quinine dihydrochloride and quinine sulfate are used as an antiprotozoal agent that acts on all types of malarial plasmodia. Quinidine sulfate is used as antiarrhythmic for tachycardia, atrial fibrillation; tincture, decoction - as an appetite stimulant and digestive aid. The content of the sum of alkaloids in the bark is not less than 6,5%, of which 30-60% are quinine-type alkaloids. Alkaloids accumulate in the parenchyma of the cortex in the form associated with quinic acid. The content of quinic acid reaches 5-8%. Of the other substances of cinchona bark, quinovine (up to 2%) should be noted - a bitter glycoside that splits during hydrolysis into quinic acid and a carbohydrate - quinovose. Anthraquinones, characteristic of the Rubiaceae family, are represented in the bark by tetrahydroxyanthraquinone. Application in medicine. Since time immemorial, local residents of South America have known about the action of decoction and cinchona bark extract. In scientific medicine, the therapeutic effect of cinchona bark became known after the wife of the Peruvian viceroy, Countess Anna Tsinkhonati, was cured of malaria, after whom the plant was named. The bark of the cinchona tree was brought to Europe in 1639. In 1820, Pelletier and Caventa isolated quinine and cinchonine from the bark. A number of other substances have been isolated. Of all the cinchona alkaloids, the most important in practical terms are quinine and quinidine. Quinine causes depression of the central nervous system, in large doses it has a deafening effect, causes tinnitus, headache, dizziness, depresses thermoregulation, lowering body temperature, especially in febrile conditions. Large doses of quinine adversely affect vision. An important side of the action of quinine is the ability to reduce the excitability of the heart muscle, lengthen the refractory period, inhibit the conduction of impulses along the His bundle and reduce myocardial contractility. The sinus node is more resistant to the action of quinine than the secondary centers of excitation in the heart muscle, where heterotropic impulses arise under pathological conditions. Therefore, small doses of quinine can eliminate the occurrence of excitations that cause atrial fibrillation. Quinine increases uterine contractions in the last period of pregnancy. This effect is manifested after taking toxic doses, so attempts to use quinine for abortive purposes often end in severe poisoning. Quinine is rapidly absorbed and quickly excreted from the body. The main property of quinine, thanks to which it has firmly entered medicine, is its ability to inhibit the vital activity of erythrocyte forms of malarial plasmodia. Quinine has no effect on gametocytes and tissue forms of the causative agent of malaria. The pharmacological action of quinidine is in many respects similar to quinine. This is due to their chemical relationship. Quinidine is the dextrorotatory isomer of quinine. Like quinine, it has antipyretic properties, increases uterine contractions. However, it causes a more distinct bradycardia. Under the influence of quinidine in the heart muscle, a number of changes occur: a lengthening of the refractory period, a decrease in excitability, a decrease in heart rate associated with the direct action of quinidine on the sinus node, a slowdown in the conduction of impulses, especially atrioventricular conduction (the P-Q interval on the electrocardiogram lengthens), lengthening of the electrical systole (long QT interval). In addition, quinidine improves coronary circulation, dilates the vessels of the heart. Due to the above properties, quinidine eliminates or slows down atrial fibrillation. Quinidine acts on the biochemical processes occurring in the heart muscle. It leads to a violation of the exchange of phosphorus macroergic compounds; reduces their formation and slows down the breakdown in tissues, lowers the adenosine triphosphatase activity of the heart muscle. It is believed that quinidine is in competition with acetylcholine for biochemical receptors that respond to endogenous acetylcholine; this explains the ability of quinidine to weaken the effect of acetylcholine on the cardiac, skeletal and smooth muscles. Quinine preparations are used for malaria. Quinine is also prescribed for atrial fibrillation, paroxysmal tachycardia, extrasystoles. Quinine weakens heart contractions even at therapeutic doses. Therefore, digitalis is sometimes prescribed beforehand. Quinine is not prescribed to patients with circulatory failure II-III degree, with all forms of heart block, as well as in the presence of inflammatory processes. Treatment with quinine requires special care, especially when it comes to intravenous administration of the drug. It is necessary to establish the patient's response to the introduction of quinine by careful questioning. If the patient has idiosyncrasy to quinine, intravenous administration should be avoided. Complications are possible during intravenous administration of quinine. With a sharp drop in blood pressure, frequent weak filling of the pulse, an isotonic solution of sodium chloride and various tonic substances strychnine, camphor, caffeine, ephedrine, adrenaline, corazole are injected under the skin simultaneously with quinine. Quinine has a local irritating effect, it is recommended to inject it deep into the subcutaneous tissue in an isotonic sodium chloride solution and in weakly concentrated solutions. Quinidine is widely used in tachyarrhythmias atrial fibrillation arising from various causes (with mitral stenosis, cardiosclerosis, thyrotoxicosis and various intoxications). Quinidine is especially effective in paroxysmal tachycardia, paroxysms of atrial fibrillation and extrasystoles. Quinidine is also used to prevent atrial fibrillation, for example, with mitral stenosis, accompanied by frequent atrial extrasystoles, with atrial flutter, attacks of paroxysmal tachycardia, but in these cases it acts worse than with atrial fibrillation. Authors: Turova A.D., Sapozhnikova E.N.
Cinchona reddish (reddish cinchona), Cinchona succirubra. Recipes for use in traditional medicine and cosmetology Ethnoscience:
Cosmetology:
Attention! Before use, consult with a specialist!
Cinchona reddish (reddish cinchona), Cinchona succirubra. Tips for growing, harvesting and storing The red cinchona (Cinchona succirubra) is a large evergreen tree that is used to produce kinin, used to treat malaria. Tips for growing, harvesting and storing cinchona reddish: Cultivation:
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It is important to note that cinchona reddish may contain certain alkaloids that may cause unwanted effects. Therefore, it is recommended to use this plant only under the supervision of an experienced physician or homeopath. We recommend interesting articles Section Cultivated and wild plants: ▪ Play the game "Guess the plant from the picture" See other articles Section Cultivated and wild plants. Read and write useful comments on this article. Latest news of science and technology, new electronics: Energy from space for Starship
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