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What accident led to the invention of Viagra? Detailed answer

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What accident led to the invention of Viagra?

In 1992, the pharmacological company Pfizer was conducting clinical trials of its new drug, sildenafil citrate, which was being developed for the treatment of heart disease. The drug did not have a significant effect on blood circulation in the heart muscle (myocardium) and blood pressure. However, many of the men who took part in the testing did not want to return the pills, as they noticed an improvement in the quality of their erections. This is how Viagra was invented.

Authors: Jimmy Wales, Larry Sanger

 Random interesting fact from the Great Encyclopedia:

How far is the nearest star from us?

From the star Proxima in the constellation Centaurus, light flies to us for 4,22 years. True, you cannot see it with the naked eye, it is too weak. But next to it is the bright Alpha Centauri, which is 4,38 light years away.

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Random news from the Archive

Protons are heavier than a neutron star 28.02.2019

Neutron stars are among the densest objects in the universe. They withstand such intense pressure that one teaspoon of star material would weigh about 15 times more than the moon. But it turned out that there are things in which the pressure is even greater. And these are protons.

Physicists at the Massachusetts Institute of Technology (MIT) for the first time were able to calculate the pressure distribution in a proton and found that the core of the particle is under pressure that exceeds the pressure in neutron stars.

To measure the pressure in protons, scientists bombarded hydrogen targets with electron beams. There, electrons interacted with quarks inside protons from the target. The physicists then determined the pressure distribution across the proton based on how the electrons scatter in the target. Their results showed that the highest pressure in a proton is about 10^35 pascals, which is 10 times the pressure inside a neutron star.

It turns out that quarks and gluons in the center of the proton create a significant outward pressure, and closer to the edges there is a confining counter pressure. That is, the nucleus pushes from the center of the proton, while the outer regions push inward. It is this counter pressure that stabilizes the overall structure of the proton.

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