Ambiguous fame and unambiguous talent. Meaning, origin, examples of the use of phraseological units

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Winged words, phraseological units. Meaning, history of origin, examples of use

Winged words, phraseological units

Directory / Winged words, phraseological units

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Ambiguous fame and unambiguous talent

Igor Severyanin

Phraseologism: Ambiguous fame and unambiguous talent.

Meaning: About a talented person with a dubious reputation.

Origin: From the poem "Poem outside the subscription" (1912) by the poet Igor Severyanin (pseudonym of Igor Vasilyevich Lotarev, 1887-1941), in which he speaks of himself as a poet.

Random phraseology:

Memory of the future.

Meaning:

About events, phenomena of the past, which may find their continuation in the future.

Origin:

From German: Erinnerungen an die Zukunft. The title of a book (1968) by the German author Erich von Däniken, as well as a documentary film (1979, directed by H. Reinl) based on this book. Erich von Däniken speaks in this film about the possibility of aliens visiting the Earth in antiquity and gives his arguments in favor of this hypothesis.

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Random news from the Archive

immune switch gene 19.12.2012

Researchers have discovered a key gene that is responsible for the functioning of the immune system. It turns out that when just one gene called Bcl11a is turned off, the cells of the adaptive immune system stop developing and fighting bacteria and other pathogens.

An adaptive immune system is very important because it protects a person from re-infection with various infectious diseases. It is thanks to this system that all vaccines are effective and many diseases, such as, for example, polio, are defeated. In addition, the immune system recognizes similar strains, such as influenza, and the disease with a new strain is easier. Finding a gene that can turn adaptive immunity on and off could be both a powerful cure and a deadly bioweapon.

Previously, scientists have learned that Bcl11a is essential for the development of certain immune cells in mouse embryos. In the new study, they looked at the role of this gene in adult mice. Researchers at the Wellcome Trust Sanger Institute knocked out the Bcl11a gene and studied the development of immune system cells. The scientists were surprised when they found that after the gene was switched off, the adaptive immune system stopped producing immune B, T and NK cells.

Thus, for the first time, scientists have found a single gene that must be active for the adaptive immune system to function. Thanks to this discovery, scientists will be able to understand how our immune system works, how to suspend its work or, on the contrary, activate it.

The exclusive function of the Bcl11a gene is due to the fact that it is responsible for the production of a protein, without which the progenitor cells of the adaptive immune system die. On the other hand, Bcl11a hyperactivity causes lymphoma - the most dangerous type of cancer. Bcl11a also plays a role in the development of oxygen-carrying red blood cells: in 2011, researchers had already demonstrated how knocking out the Bcl11a gene could cure sickle cell anemia in mice.

The discovery of the importance of the Bcl11a gene will allow for a variety of experiments, in particular the study of the behavior of human immunity in laboratory mice. In addition, the discovery may help develop effective methods of treating cancer. On the other hand, Bcl11a can also be used as a weapon: turning off this gene with a modified virus, for example, will make a person extremely susceptible to dozens of diseases that are considered relatively safe.

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