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Sleep supports antioxidant processes in the body

25.07.2018

Sleep is a state that is natural not only for humans, but also for almost all animals, starting with insects. While we sleep, our body rests, the brain processes the information received during the day, our health is strengthened. It turned out that sleep also plays an important role as an antioxidant agent: it reduces oxidative stress, and the latter, on the contrary, can cause sleep disturbances.

This two-way relationship between the two processes was identified by a team of scientists from Columbia University (New York, USA). Biologists conducted a study in which they observed mutant types of Drosophila fruit flies. Insects bred in the laboratory sleep very little. Scientists have determined that due to lack of sleep, these fruit flies are subject to oxidative stress to a greater extent than their relatives who do not have sleep problems.

Oxidative stress develops when free oxygen radicals (molecules without one electron) damage healthy cells in the body. Molecules can start a chain reaction - and in this case, a serious disease develops: from diabetes to cancer. In addition, oxidative stress damages neurons, triggering pathological responses. Free radicals are inevitably formed in the body, in a certain amount they are even useful: they help fight bacteria. However, if there are too many of them, they themselves become harmful to health. Their number increases under the influence of various factors: stress, poor environment, medication, heavy physical activity.

As a rule, antioxidants help to cope with these radicals - nutrients that negate the chemical reactions triggered by free oxygen molecules. These substances can be obtained from foods - mainly fruits and vegetables - and from special vitamins. Now sleep can also be added to the list of "antioxidants".

Researchers have found that one of the functions of sleep is to protect against oxidative stress. Based on this, the authors also suggested that oxidative stress may also affect sleep. Testing this hypothesis, they stimulated the genes of the antioxidant system in Drosophila, thereby reducing oxidative stress. This change literally put the flies to sleep. Otherwise, the unpleasant state caused insomnia.

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Determining the authenticity of coffee 30.01.2021

There are two main varieties of coffee - the more expensive Arabica and the cheaper Robusta. To get the best price, producers often mix beans of two varieties, believing that after roasting it will be very difficult to determine their ratio.

In laboratory conditions, chromatography and spectroscopy methods are used to authenticate coffee varieties, which are costly and time consuming. With a simpler and cheaper version of extraction with chloroform, it is not possible to determine all the necessary types of compounds.

Scientists from the University of Guelph and the National Research Council of Canada have developed a new method to quantify the composition of coffee in a package based on the nuclear magnetic resonance (NMR) method.

In particular, using NMR, the researchers successfully identified all 12 compounds that are commonly studied in tests of pure coffee, and whose concentrations differ depending on the variety and geographical origin of the beans - caffeine, trigonelline, 3- and 5-caffeylquinic acid, lipids, cafestol, nicotinic acid, N-methylpyridinium, formic acid, acetic acid, kahweol and 16-O-methyl capestol.

Elevated amounts of 16-O-methyl capestol (16-OMC) are unique to Robusta and kahweol to Arabica.

They found a direct correlation between the contents of these two compounds in coffee blends and the bean ratio of the two varieties. The scientists measured the levels of 16-OMC, kahweol and other aromatic compounds in 292 samples from manufacturers around the world.

The discrepancy between the results for samples whose mixture composition was known was no more than 15% even at relatively low concentrations of the two indicator compounds.

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