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The brain processes what is learned in REM sleep

24.05.2016

Sleep the night before the exam. But how to do this if noisy neighbors interfere? Just ask them not to disturb your theta rhythms during REM sleep - it's only an hour or two.

In a study published today in the journal Science, neuroscientists tested exactly how the REM phase affects our memory. During REM sleep, the mammalian brain emits theta waves. Influencing the light on the neurons responsible for stimulating the production of these waves, the scientists "turned off" the radiation, and at the same time the animals did not wake up.

Turning lights on and off in the brains of mice is one of the most promising ways to study the brain today. This time, scientists undertook to study the relationship between sleep and memory. It is known that sleep deprivation is bad for health, so conducting such experiments on humans, alas, is unethical - and again, optogenetics in mouse heads helps scientists.

It turned out that the mice, whose sleep was not disturbed by anything, the next day perfectly reproduced what they had learned the day before. The same animals that were "turned off" theta rhythms experienced memory problems - they did not recognize the place where they received an electric shock yesterday, and went there without fear.

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Latest news of science and technology, new electronics:

Machine for thinning flowers in gardens 02.05.2024

In modern agriculture, technological progress is developing aimed at increasing the efficiency of plant care processes. The innovative Florix flower thinning machine was presented in Italy, designed to optimize the harvesting stage. This tool is equipped with mobile arms, allowing it to be easily adapted to the needs of the garden. The operator can adjust the speed of the thin wires by controlling them from the tractor cab using a joystick. This approach significantly increases the efficiency of the flower thinning process, providing the possibility of individual adjustment to the specific conditions of the garden, as well as the variety and type of fruit grown in it. After testing the Florix machine for two years on various types of fruit, the results were very encouraging. Farmers such as Filiberto Montanari, who has used a Florix machine for several years, have reported a significant reduction in the time and labor required to thin flowers. ... >>

Advanced Infrared Microscope 02.05.2024

Microscopes play an important role in scientific research, allowing scientists to delve into structures and processes invisible to the eye. However, various microscopy methods have their limitations, and among them was the limitation of resolution when using the infrared range. But the latest achievements of Japanese researchers from the University of Tokyo open up new prospects for studying the microworld. Scientists from the University of Tokyo have unveiled a new microscope that will revolutionize the capabilities of infrared microscopy. This advanced instrument allows you to see the internal structures of living bacteria with amazing clarity on the nanometer scale. Typically, mid-infrared microscopes are limited by low resolution, but the latest development from Japanese researchers overcomes these limitations. According to scientists, the developed microscope allows creating images with a resolution of up to 120 nanometers, which is 30 times higher than the resolution of traditional microscopes. ... >>

Air trap for insects 01.05.2024

Agriculture is one of the key sectors of the economy, and pest control is an integral part of this process. A team of scientists from the Indian Council of Agricultural Research-Central Potato Research Institute (ICAR-CPRI), Shimla, has come up with an innovative solution to this problem - a wind-powered insect air trap. This device addresses the shortcomings of traditional pest control methods by providing real-time insect population data. The trap is powered entirely by wind energy, making it an environmentally friendly solution that requires no power. Its unique design allows monitoring of both harmful and beneficial insects, providing a complete overview of the population in any agricultural area. “By assessing target pests at the right time, we can take necessary measures to control both pests and diseases,” says Kapil ... >>

The threat of space debris to the Earth's magnetic field 01.05.2024

More and more often we hear about an increase in the amount of space debris surrounding our planet. However, it is not only active satellites and spacecraft that contribute to this problem, but also debris from old missions. The growing number of satellites launched by companies like SpaceX creates not only opportunities for the development of the Internet, but also serious threats to space security. Experts are now turning their attention to the potential implications for the Earth's magnetic field. Dr. Jonathan McDowell of the Harvard-Smithsonian Center for Astrophysics emphasizes that companies are rapidly deploying satellite constellations, and the number of satellites could grow to 100 in the next decade. The rapid development of these cosmic armadas of satellites can lead to contamination of the Earth's plasma environment with dangerous debris and a threat to the stability of the magnetosphere. Metal debris from used rockets can disrupt the ionosphere and magnetosphere. Both of these systems play a key role in protecting the atmosphere and maintaining ... >>

Solidification of bulk substances 30.04.2024

There are quite a few mysteries in the world of science, and one of them is the strange behavior of bulk materials. They may behave like a solid but suddenly turn into a flowing liquid. This phenomenon has attracted the attention of many researchers, and we may finally be getting closer to solving this mystery. Imagine sand in an hourglass. It usually flows freely, but in some cases its particles begin to get stuck, turning from a liquid to a solid. This transition has important implications for many areas, from drug production to construction. Researchers from the USA have attempted to describe this phenomenon and come closer to understanding it. In the study, the scientists conducted simulations in the laboratory using data from bags of polystyrene beads. They found that the vibrations within these sets had specific frequencies, meaning that only certain types of vibrations could travel through the material. Received ... >>

Random news from the Archive

Synthetic molecules destroy allergies 10.11.2012

Scientists have figured out how a synthetic molecule can destroy the complexes that cause allergic reactions. This discovery could lead to a very powerful development of fast-acting drugs to treat a range of acute allergic reactions. The research was carried out by scientists from Stanford University Medical School and the University of Bern, Switzerland.

A new inhibitor disarms IgE antibodies - key players in acute allergies. It separates antibodies from their chemical partners, molecules called FcRs.

"It would be incredibly fortunate if you could quickly turn off IgE antibodies in the midst of an acute allergic reaction," said Dr. Ted Zardecki, professor of structural biology and research team leader. However, it turned out that the inhibitor used by scientists does just that.

A wide variety of allergens, ranging from pollen to peanut butter, can cause an allergy in a matter of seconds by provoking IgE antibodies. The new synthetic inhibitor destroys the complex that binds IgE to FcR - the cells responsible for the reaction. Breaking that connection is the veritable Holy Grail for dealing with allergies.

"If you separate IgE from FcR on the surface of mast cells - immune cells of connective tissues - this will save a person from an allergic reaction," the authors of the study say.

As a result, a protein macromolecule was created, named by the creators of DARPin E2-79. It not only blocks the formation of new IgE-FcR complexes, but also actively decomposes already formed ones. And all this happens in just a few seconds. In addition, the molecule turned out to be small, but effective, which was a big surprise. The fact is that drug developers usually expect large macromolecules. And it seemed to them that E2-79 would turn out to be less powerful than small molecules of inhibitors, and would hardly be able to destroy the complexes. So the fact that the E2-79 worked so well came as a surprise. In addition, small molecules are more suitable for oral administration, as well as cheaper and easier to manufacture than large macromolecules.

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