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Blood vessels are easier to print

21.09.2012

XNUMXD blood vessels with a complex tree structure are printed in seconds. The new technology promises a real breakthrough in regenerative medicine. The fact is that scientists can already grow various types of tissues and even entire organs, but recreating the most complex system of large vessels and small capillaries has so far remained a difficult task.

Nanoengineers at the University of California have developed a new technology that creates micro-scale, three-dimensional capillary structures in seconds. The raw material for artificial vessels is a non-traumatic biocompatible hydrogel. The vessels are printed using Dynamic Optical Projection Stereolithography (DOPsL) technology developed by Professor Chen's laboratory.

DOPsL made it possible for the first time to print XNUMXD vessels relatively easily and quickly. Similar modern technologies, such as photolithography and microcontact printing, can only create a two-dimensional structure, and even then only in a few hours.

Stereolithography is well known and widely used for printing large parts. DOPsL technology works in exactly the same way, but at the micro level. It allows you to create microscopic objects of complex shape, including three-dimensional vessels. This is extremely important, since all the current successes in regenerative medicine associated with the cultivation of large organs and complex tissues rested precisely on the problem of blood supply.

The new technology allows not only to copy the natural structure of capillaries, but also to create more complex patterns, such as spirals and hemispheres. In the future, this quality can be used to install sensors, injectors, etc. in artificially grown organs.

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Random news from the Archive

warm windows 06.11.2004

Heat-reflecting coatings for glass have been known for a long time and are often used in the windows of south-facing buildings.

In hot weather, they reject the infrared rays of the Sun, maintaining an acceptable temperature in the rooms. But, unfortunately, in winter, when heating by the sun's rays would not hurt, these glasses continue to reflect heat.

This is not how a new glass coating developed by English chemists from University College London and the University of Liverpool behaves. Several decades ago, scientists discovered that vanadium dioxide, which transmits infrared rays at ordinary temperatures, becomes opaque to these rays if it is heated above 68 degrees Celsius.

English chemists, by adding traces of tungsten to vanadium dioxide, were able to reduce the transition temperature to 29 degrees Celsius. When newly coated glass is heated to this temperature, it begins to reflect heat rays. In the meantime, the temperature of the glass is lower, it passes them and heats the room. It is estimated that on sunny winter days, apartments on the south side of buildings with such window panes can save up to half of heating costs.

The coating is applied by keeping the freshly made, still hot sheet glass in an atmosphere of two gases - vanadium oxytrichloride and tungsten hexachloride at atmospheric pressure.

Two problems must be overcome before mass production of the new glass can begin. First, the self-adjusting coating gives the glass a yellowish-greenish tint. To neutralize it, blue dyes can be introduced into the glass. Secondly, the new coating can be washed off when washing windows. Apparently, it will be necessary to protect the heat-regulating glass on both sides with sheets of ordinary glass.

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