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Lonely and unhappy people age faster than smokers

03.10.2022

According to a new study by Deep Longevity, mental health affects the rate of aging more than smoking and certain diseases. Especially vulnerable to premature aging were lonely and unhappy people who do not sleep well.

With age, various molecular damage accumulates in our cells, contributing to the overall aging of the body and the development of various diseases. In some people, these molecular processes are more intense than in others. This condition is commonly referred to as accelerated aging.

Fortunately, the increase in the rate of aging can be detected even before the first consequences appear. Deep Longevity is developing models that predict the rate of aging based on epigenetic changes, end-of-chromosome changes (telomeres), gene expression, and concentrations of various metabolites. These models can be used to develop anti-aging therapies. However, now a team of American and Chinese scientists have shown that any such therapy should not only focus on physical but also mental health.

As a result, the researchers found signs of accelerated aging in people with a history of stroke, liver and lung disease, in smokers, and in people who are in a vulnerable mental state. It turned out that the feeling of loneliness and unhappiness, anxiety and poor sleep increase the biological age of a person even more than smoking. Other factors associated with the acceleration of aging include living in rural areas, which is likely due to the low availability of medical services.

Thus, according to scientists, the psychological aspect of aging should not be neglected either in research or in the development of anti-aging therapy. Mental and psychosocial conditions are among the most reliable markers of health and quality of life, but they are practically not taken into account in the modern healthcare system.

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Random news from the Archive

Gold nanoparticles were synthesized using mimioza 22.07.2017

An international team of researchers has learned how to synthesize gold-containing nanoparticles using bacteria that live inside the bashful mimosa (Mimosa pudica).

The resulting compounds have pronounced bactericidal properties. According to the authors of the study, their work can be useful for creating new drugs that fight antibiotic-resistant bacteria.

"The present study proposes a fast and environmentally friendly method for the synthesis of gold-containing nanoparticles using the new symbiotic bacterium Aneurin Bacillus migulanus 14, which lives in bashful mimosa. The effectiveness of the new substance in combating pathogens is shown by the example of a significant reduction in the activity of the pathogen Pseudomonas aeruginosa," says in an article published in the journal Environmental Toxicology and Pharmacology.

Due to the widespread use of antibiotics, there are now more and more drug-resistant microorganisms in the world, so people are looking for new ways to fight bacteria. Studies show that various metal nanoparticles, especially those containing silver and gold, have strong antibacterial properties. But, unfortunately, the chemical synthesis of such compounds is not only very expensive, but also unsafe, since it involves the use of toxic elements hazardous to human health and the environment.

In the new work, the synthesis process itself using the bacterium Aneurin Bacillus migulanus 14 was a multi-step process, but after optimization by the researchers, it can be completed in as little as 20 minutes. At the same time, the synthesis does not require high temperatures, complex and expensive equipment, or the use of toxic reagents.

The researchers tested the antimicrobial activity of the new compounds against a series of pathogenic bacteria. As a result, it turned out that gold helps very well against various infections. Nanoparticles coped best with Pseudomonas aeruginosa P. Aeruginosa, Escherichia coli E. Coli, Staphylococcus aureus S. aureus, hay bacillus B. Subtilis, and Klebsiella pneumoniae K. Pneumoniae.

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