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OCCUPATIONAL SAFETY AND HEALTH
Instruction on labor protection for a pharmacist-analyst and a pharmacist-technologist who controls the quality of medicines
Occupational Safety and Health / Standard instructions for labor protection Safe Operation 1. General safety requirements 1.1. This instruction provides for the prevention of exposure to hazardous and harmful production factors. Dangerous factors affecting the pharmacist-analyst and the pharmacist-technologist are the malfunction of electrical appliances and apparatus, careless work with concentrated acids, alkalis, reagents and other aggressive liquids, glassware, various devices used in the process of monitoring the quality of medicines (refractometer, scales, FEK, microscope, pH meter, alcohol meter, plates for qualitative reactions, burettes, flasks, jars, pipettes, etc.). Harmful for the pharmacist-technologist and pharmacist-analyst are the possibility of poisoning, allergization, exposure to irritating and poisonous substances, increased dustiness with medicinal substances that are formed in the process of monitoring the quality of medicines. 1.2. The instruction applies to all pharmacists-analysts and pharmacists-technologists who control the quality of medicines in pharmacies and is a guide in the preparation of instructions that should be developed taking into account local characteristics and posted in a conspicuous place in this area of work. 1.3. In their work, the pharmacist-analyst and the pharmacist-technologist are guided by regulatory documents, as well as the current rules for the device, operation, safety and industrial sanitation when working in pharmacies and control and analytical laboratories. 1.4. Individuals with a higher pharmaceutical education, who have undergone special training, trained in labor safety in accordance with GOST 12.0.004-79 and who have 1 electrical safety group, should be allowed to independently work on quality control of medicines. Instead of GOST 12.0.004-79, by the Decree of the USSR State Standard of November 5, 1990 No. 2797, GOST 12.0.004-90 was approved and put into effect When applying for a job, a pharmacist-analyst and a pharmacist-technologist must undergo an introductory safety briefing, as well as an initial briefing at the workplace, and then every six months a repeated briefing, which should be recorded in the journal. 1.5. In the process of quality control of medicinal products, the pharmacist-analyst and the pharmacist-technologist must comply with the internal labor regulations, use sanitary overalls, safety shoes, personal protective equipment and other safety devices in accordance with the current standards for their issuance. 1.6. The pharmacist-analyst and the pharmacist-analyst and the pharmacist-technologist are obliged to comply with the standard fire safety rules, to contribute to the prevention of fires and explosions. 1.7. The pharmacist-analyst and the pharmacist-technologist must know and observe the rules of personal hygiene, keep gowns and caps clean, wash their hands with warm water and soap and a brush. They must systematically undergo a medical preventive examination in the prescribed manner. 1.8. The pharmacist-analyst and the pharmacist-technologist are personally responsible for violation of the requirements of this instruction. Persons who have failed to comply with or violate labor protection instructions are subject to disciplinary action in accordance with the internal labor regulations and, if necessary, an extraordinary examination of knowledge of labor protection issues. 2. Safety requirements before starting work 2.1. The pharmacist-analyst and the pharmacist-technologist are obliged to prepare their workplace for safe work, bring it to a proper sanitary condition, and subject it to wet cleaning. 2.2. Before starting work, the pharmacist-analyst and pharmacist-technologist, accepting the workplace, must check the serviceability of the instruments and other equipment, mechanization and utensils, various devices and other items of workplace equipment. 2.3. The workplace should not contain equipment, instruments, fixtures, utensils and other auxiliary materials that are not used in the work. 3. Safety requirements during work 3.1. The pharmacist-technologist and the pharmacist-analyst during work should not be in a hurry, take prescriptions and dispense medicines in accordance with safe techniques and methods of analysis. 3.2. When using various devices and devices, mechanization and devices, the pharmacist-analyst and pharmacist-technologist must be guided by the rules (instructions) set forth in the technical passports attached to the devices and devices. They should not use these or other devices without prior training in working with them. 3.3. When turning on electrical appliances and other electrical equipment, the pharmacist-analyst and pharmacist-technologist must check that the voltage of the device specified in the passport matches the voltage in the network, as well as the presence of grounding for those that have metal cases. They must not switch on with wet hands. All heating devices (electric stoves, etc.) must be installed on asbestos and other heat-insulating materials. 3.4. To prevent hand cuts, the pharmacist-analyst and pharmacist-technologist must monitor the integrity of glass instruments, equipment and utensils (burettes, pipettes, cylinders, flasks, funnels, stem-glasses, mortars, etc.) and prevent the use of broken objects in work. 3.5. Upon receipt for control of medicinal products containing poisonous or narcotic substances, the pharmacist-analyst or pharmacist-technologist must immediately begin to control their quality. 3.6. In the process of quality control of such medicines, as well as when using toxic and potent reagents, the pharmacist-analyst and pharmacist-technologist must comply with safety regulations. When performing organoleptic quality control of medicinal products containing poisonous, narcotic and potent substances, as well as medicinal products for external use, taste tests should not be allowed. 3.7. If it is necessary to heat solutions with toxic substances, it should be carried out only in round-bottom flasks. 3.8. Washing and processing of dishes in which medicines are tested or reagents with poisonous or narcotic substances are used should be carried out separately from other dishes under the supervision of a pharmacist-analyst and a pharmacist-technologist. 3.9. After finishing work with poisonous and narcotic substances, the pharmacist-analyst and the pharmacist-technologist should thoroughly wash their hands, and if necessary, brush their teeth and rinse their mouths. If workwear and towels are contaminated with potent and toxic substances, the pharmacist-analyst and pharmacist-technologist must immediately change them, take measures to neutralize them, and then transfer them to the laundry. 3.10. The pharmacist-analyst and pharmacist-technologist should drain spent silver nitrate solutions into special dark glass bottles for further regeneration and store in a lockable cabinet. 3.11. When working with flammable substances, the pharmacist-analyst and the pharmacist-technologist must be careful to perform these works away from fire. If it is necessary to heat flammable substances, it should be done on water baths or electric stoves with a closed coil. 3.12. Hangers with explosive, odorous and volatile substances must be tightly closed by the pharmacist-analyst and the pharmacist-technologist. When checking the quality of medicines, which include ether, chloroform, etc., the liquid should be agitated carefully, directing the neck (bottles, flasks, test tubes) away from you to avoid ejection of the solution. 3.13. After working with coloring, odorous substances, the pharmacist-analyst and the pharmacist-technologist should wash their hands with warm water, soap and a brush. 3.14. Substances with a pungent odor, flammable, alkalis, volatile, flammable, as well as hot liquids, the pharmacist-analyst and pharmacist-technologist should not be refrigerated. 3.15. To avoid fire, the pharmacist-analyst and the pharmacist-technologist must keep flammable substances near an open fire. 3.16. The pharmacist-analyst and the pharmacist-technologist should not lift and carry loads weighing more than 15 kg alone. 3.17. When working with liquids in cylinders, it is necessary to use cylinder dumpers, it is not allowed to lift cylinders and carry them in front of you. 3.18. When working with concentrated acids, caustic alkalis (phenol, formalin, ammonia solution) and other aggressive liquids, the pharmacist-analyst and pharmacist-technologist should use a cylinder for measuring them (and not a pipette!), As well as use oilcloth aprons, rubber gloves, respirators , goggles. Work should be carried out in a fume hood, with the doors lowered and ventilation turned on. When working in a fume hood, do not keep your head under the draft. 3.19. The pharmacist-analyst and the pharmacist-technologist must be careful when working with hydrogen peroxide, not allowing it to be heated in closed vessels; with potassium permanganate, berthollet salt and other strong oxidizing agents, avoiding contact with reducing agents and acids. When diluting concentrated acids, acids should be poured into water, and not vice versa. 3.20. If it is necessary to wash with a chromium mixture, the pharmacist-analyst and the pharmacist-technologist must first wash the dishes with water to avoid explosion and splashing. 3.21. The pharmacist-analyst and the pharmacist-technologist should not allow the contents of flasks and test tubes tightly closed with stoppers to be heated. Heating of the liquid in the test tube should be started from the upper layers, gradually moving to the lower ones. 3.22. For sampling liquids, the pharmacist-analyst and the pharmacist-technologist should use a pipette with a pear, and not suck it into the pipette with their mouths. Small containers should not be sampled, but a small amount of liquid must first be drained. 3.23. When determining the smell of the drug, you should direct the vapors with the movement of the hand "toward yourself", and not inhale intensively. 3.24. The pharmacist-analyst and the pharmacist-technologist should protect their hands from cuts; when corking the bottle, hold it by the neck, carefully screwing in the cork. 3.25. To prevent eye strain associated with measuring liquid from burettes and pipettes, the pharmacist-analyst and pharmacist-technologist should turn on additional local lighting at the workplace. To prevent overwork and damage to vision when using a refractometer and a microscope, the pharmacist-analyst must work alternately with one or the other eye. He should not close the idle eye. 3.26. The pharmacist-analyst and the pharmacist-technologist must constantly maintain their workplace in proper sanitary condition. 4. Safety requirements in emergency situations 4.1. The victim or eyewitness of the accident must immediately notify the appropriate supervisor of any work-related accident. The manager must organize first aid for the victim, his delivery to a medical institution, inform the head of the pharmacy, the labor protection engineer or the person performing his functions, and the trade union committee about what happened, keep the situation at the workplace and the condition of the equipment as it was for investigation at the time of the incident, if it does not threaten the life and health of the surrounding workers and does not lead to an accident. 4.2. In the event of a spill of acids, alkalis, and other aggressive reagents, the pharmacist-analyst and pharmacist-technologist must take the necessary measures to eliminate the consequences: open windows, ventilate the room, and carefully remove the spilled liquid. If alkali is spilled, then it must be covered with sand (or sawdust), then remove the sand (or sawdust) and fill this place with highly diluted hydrochloric acid (or acetic acid). After that, remove the acid with a rag, wash the table with water. If acid is spilled, then it must be covered with sand (you cannot fill it with sawdust), then remove the soaked sand with a shovel, cover with soda, remove the soda and rinse this place with plenty of water. 4.3. In case of burns with acid, alkali or other aggressive reagents, wash off the affected surface with a strong stream of water, and then treat accordingly. 4.4. In the event of a fire, the pharmacist-analyst and the pharmacist-technologist must take measures to limit its spread (turn off electrical appliances and apparatus, use fire extinguishers), create conditions for extinguishing it, ensure the safety of people and preserve material values. 4.5. In case of other emergencies, the pharmacist-analyst and the pharmacist-technologist must take measures to evacuate material assets in accordance with the evacuation plan in case of fire or other natural disasters. 5. Safety requirements at the end of work 5.1. The pharmacist-technologist and the pharmacist-analyst must turn off the devices and apparatus that they used in the process of work (electric stove, water bath, etc.). 5.2. At the end of the work, the pharmacist-analyst and the pharmacist-technologist must wash the table with warm water and soap, if necessary, with a disinfectant solution and comply with all the requirements of the sanitary regime. 5.3. At the end of the working day, the pharmacist-analyst and pharmacist-technologist must take off the gown, cap, safety shoes and put them in a special closet, wash their hands thoroughly and comply with all the requirements for personal hygiene of pharmacy employees. 5.4. In the event that in the course of work deficiencies in the operation or malfunction of devices, instruments and equipment are detected, the pharmacist-analyst and pharmacist-technologist must notify the pharmacy administration about this.
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