Apples promote the growth of new neurons. Free Technical Library News

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Apples promote the growth of new neurons

19.02.2021

Natural compounds found in apples and a number of other fruits can stimulate the formation of new neurons. Such results were shown by a study conducted with mouse cells. Nature has taken care of us better than we think! As it turned out, even a simple apple can greatly affect brain function.

Scientists have long known that phytonutrients (chemicals found in plants) can have positive effects on various human organs, including the brain. Researchers at the University of Queensland in the US and the German Center for Neurodegenerative Diseases have found that high concentrations of phytonutrients from apples stimulate the generation of new neurons, a process called neurogenesis.

The study found that lab-grown adult mouse brain stem cells generate more neurons when they encounter quercetin or dihydroxybenzoic acid, phytonutrients found in apples. Follow-up tests in mice showed that in various adult brain structures associated with learning and memory, stem cells proliferated and generated more neurons when the animals were given high doses of quercetin or dihydroxybenzoic acid.

The effects on neurogenesis were comparable to those observed after physical activity, which also stimulates neurogenesis.

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New ways of liver regeneration have been found 22.10.2023

Researchers in the United Arab Emirates have discovered innovative ways to restore the liver. Foreign sources report on epigenetics methods that can promote the regeneration of this important organ of the human body.

World scientists have long been looking for unknown ways to renew the cells of human internal organs. An important discovery in this area was made by a team of specialists from the UAE.

According to the researchers, an effective way to stimulate liver regeneration is to remove certain parts of the epigenome responsible for suppressing jumping genes. This method results in a redistribution of epigenetic marks.

This is explained by the fact that a form of epigenetic compensation prevents the activation of transposable elements of the genome. It blocks the regulation of gene expression by compensatory epigenetic marks. This process ensures that repressive genes are activated earlier, which helps support regeneration after surgical removal of parts of the liver, as is often the case with tumor resection.

The results open the way to a deeper understanding of liver regeneration and the unique ability of this organ to recover, which exists in all mammalian species, including humans. In laboratory experiments, deletion of the core epigenetic regulator UHRF1 in the liver of mice led to a milder response of other particles, and the organ itself was successfully restored by activating specific genes.

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