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Magnetic nano-probes for cell research

29.03.2020

Most likely, in the near future, so-called nano-bots will be actively used in practical medicine - special nanoscopic micro-robots that can be used to deliver medicinal compounds bypassing all barriers, because such things are being developed and tested now. However, the application of the standard procedure for placing nano-bots in a living cell is rather complicated, primarily from an energy point of view. Therefore, a team of scientists from the University of Toronto presented their new method of such delivery and more precise movement, as well as direct control of a nano-bot inside a cell.

The use of a standard type of such a nano-bot involves the use of a sufficiently concentrated and energy-consuming laser beam, with which you can control the movement of the robot in a cage, but with known limitations and low accuracy. This can be corrected by increasing the concentration of the beam, but at the same time, the likelihood of seriously harming the cells increases.

That is why the Toronto experts have presented their new approach to such movement by increasing the degree of magnetism of their drug delivery nano-bots. The scientists created several units of these sub-700nm micro-bots and placed them in live cancer cells - and then moved the entire system onto special chemical pallets. By observing the movement of the bots inside the cages, the specialists were able to accurately and quickly control their movement using magnetic coils installed outside the cages. With this selection, they managed to significantly increase the accuracy and responsiveness of the movement of nano-bots, which made them more efficient.

A new drug delivery system of this type is becoming more efficient and interesting in absentia, including from the point of view of the resources spent. Despite some mistakes and unfinished moments, even now such a system demonstrates a really great potential for its subsequent application in practical medicine.

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