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Bioink for 3D printing of human tissues

13.02.2020

Bioengineers from Rutgers University (USA) have developed "bioink" for 3D printing of materials that could serve as a scaffold for growing human tissues. Printed fabrics can repair or replace damaged human tissues.

In the new system, hyaluronic acid and polyethylene glycol serve as the main "ink cartridges" for 3D printing. Hyaluronic acid, a natural molecule found in many body tissues, has properties that are ideal for creating custom tissue scaffolding, but it lacks the necessary strength. So engineers at Rutgers University used modified versions of hyaluronic acid and polyethylene glycol to make a gel that is strengthened by chemical reactions and acts as a scaffold for tissue growth.

In the future, the new system will have other "ink cartridges" with various cells and ligands, which serve as binding elements for tissue cells. The system will print gel scaffolds with the right stiffness, cells and ligands, depending on the type of tissue to be obtained.

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MCP1811/12 - a family of linear regulators with ultra-low quiescent current 30.12.2019

When developing portable devices, special attention should be paid to the choice of voltage converters. They should be small, have low self-consumption, and have a minimum of passive components in the harness.

Microchip offers a solution - a new family of LDO controllers MCP1811/12.

Despite the UDFN's tiny 1mm x 1mm package, the regulator can deliver up to 300mA of output current. At the same time, the quiescent current is only 250 nA, and in the Shutdown mode it can drop to 5 nA. With these features, the MCP1811/12 is well suited for small, portable, battery powered applications.

The regulators are available with nine fixed standard output voltages: 1, 1,2, 1,8, 2,0, 2,5, 2,8, 3,0, 3,3 and 4.0 V. The voltage drop at 300 mA is 400 mV.

Another feature of the MCP1811/12 is that only one ceramic capacitor with a capacity of 1 uF is sufficient for stable operation. It takes up little space on the board and provides a stable output voltage with minimal noise.

Key features of the MCP1811/12 family:

output current up to 300 mA;
quiescent current 250 nA;
case UDFN 4-lead, SOT-23-3/5, SC70-3/5;
input voltage range 1.8...5,5 V;
output voltage range 1...4 V;
fixed voltage drop (400 mA);
binding from one ceramic capacitor 1 μF (2,2 μF).

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