Bright light improves the functioning of important genes. Free Technical Library News

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Bright light improves the functioning of important genes

30.08.2019

Bright lighting can enhance the PER2 gene, which is responsible for strengthening blood vessels and protecting against cardiovascular problems. This conclusion was made by scientists from the University of Colorado.

Exposure to light is beneficial for patients' hearts if light therapy is applied a week before surgery. Based on this connection, it is possible to create new drugs for the treatment of cardiovascular diseases, experts say.

Keeping lab rodents in bright light helped the animals increase their protection against cardiovascular disease. The result of the work of experts led to the fact that in mice the degree of damage to heart tissue after a heart attack decreased.

The PER2 gene is involved in the regulation of circadian rhythms and brain functions. Exposing it to bright light helped protect blood vessels and the heart from low oxygen levels (may be with ischemia), and also led to an increase in adenosine levels (regulates blood flow).

After experimenting with rodents, the scientists tested the effect of light therapy on healthy patients. To do this, they exposed volunteers to intense light (10 lux) for half an hour for five consecutive days.

The result of the experiment showed that light therapy increased the expression level of the PER2 gene, reduced plasma triglyceride levels, and improved metabolism.

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