Immunity of pregnant women reacts to the sex of the child. Free Technical Library News

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Immunity of pregnant women reacts to the sex of the child

14.02.2017

You can hear from women that during pregnancy they feel who is inside them, a boy or a girl. This is not fiction: some medical studies have been able to show that the well-known and not very pleasant symptoms that accompany pregnancy can be stronger or weaker depending on the sex of the unborn child.

But what is the specific reason for these differences? Amanda Mitchell (Amanda M. Mitchell) and her colleagues at Ohio State University suggested that the whole thing in immunity. Poor health often begins with inflammation, so the researchers decided to check how the inflammatory background changes during pregnancy in eighty women.

The immune system controls inflammation with the help of cytokine signaling proteins, and if a bacterial infection appears in the body, for example, immune cells release many cytokines to coordinate the attack against the pathogen. On the other hand, if the immune system is "overheated", if it maintains a smoldering inflammatory reaction from scratch, without any serious reasons, then this can be recognized by the background level of the same cytokines.

The background level of inflammatory cytokines in the blood of pregnant women did not depend on the sex of the child. But everything changed when the bacteria appeared: in women pregnant with girls, immune cells responded to infection more strongly, generating more inflammatory molecular signals. Bacteria constantly penetrate our body, and the immune system successfully reflects their attacks, preventing the development of a full-fledged infectious disease.

However, the immune response must be commensurate with the threat, and it is precisely because of the excessive zeal of the immune system that pregnant women can be more tired, suffer more from various pains, in addition, they can exacerbate the symptoms of chronic diseases, such as asthma, associated with increased immune activity. Finally, do not forget that the aggressive immune system of the mother can harm the child himself.

Why immunity becomes so active "in the presence of girls" is not yet entirely clear; perhaps the reason for this is the specific changes in the hormonal background that occur precisely when carrying a female child. But, be that as it may, both the pregnant women themselves and the doctors in whom they are observed need to take into account such features of the behavior of the immune system and take some immunosedative measures in a timely manner.

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