Silk preserves blood cells at high temperatures. Free Technical Library News

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Silk preserves blood cells at high temperatures

13.05.2016

Researchers at Tufts University in the US have found a way to stabilize blood samples for long periods of time without refrigeration - by encapsulating them in dry silk protein.

The scientists mixed purified silk protein powder extracted from silkworm cocoons with blood or plasma and dried the resulting mixture. The resulting films were stored at a temperature of 22-45 degrees Celsius. After a certain time, the blood samples were successfully restored by dissolving the film in water and are ready for analysis.

Blood biomarkers in this case can be successfully assessed even after storage for 84 days at temperatures up to 45 degrees Celsius. This provides better protection than the current approach of drying the sample on paper, especially at the elevated temperatures that can occur during overseas shipping and during the summer.

"This approach should facilitate the collection of outpatient blood tests for disease screening and monitoring purposes, especially for socially vulnerable populations, as well as to meet the needs of researchers and clinicians who do not have access to a centralized testing system. For example, the method will be useful for large-scale epidemiological studies in remote areas,” explains project leader David L. Kaplan.

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