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One injection will relieve nicotine addiction

18.03.2016

Quitting smoking is not an easy task, but now scientists have created an anti-nicotine vaccine, which in the future can help a person get rid of this habit in just one shot.

Why is it so difficult to quit smoking? It's all about nicotine, which is highly addictive, and a new vaccine could help a smoker's body attack nicotine molecules before they reach the brain, thereby removing their effect along with the person's urge to smoke.

The anti-nicotine vaccine idea is not new. For the first time they started talking about it a couple of years ago, but then it worked only on 30% of the subjects. Now researchers have improved it by changing the molecules that alert the immune system and thus make it attack nicotine. With the right concentration of carrier proteins and nicotine molecules, the mice developed an active antibody response, meaning the vaccine worked. In addition, when given a second dose of nicotine, vaccinated mice had an extremely reduced and blunted response to this chemical.

In future studies, the scientists plan to study the physical dynamics between different vaccine molecules and the immune system to determine the concentration of antibodies needed for the vaccine to work properly.

While the anti-nicotine vaccine is not yet commercially available, studies show that it can be extremely effective. Moreover, a similar technique could be used to treat other addictions, for example, the same researchers are working on an anti-opioid drug right now.

It is worth recalling how smoking can affect not only your body, but also your genes.

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Random news from the Archive

Waves of sand obey the laws of mathematics 19.01.2022

Sand waves with a wavelength of 30 centimeters to several meters are known as mega ripples: they are in size between the usual beach ripples and full-fledged dunes.

In addition to their size, a key characteristic of megaripples is the arrangement of grains - large particles are always on top of small ones. This mixture is never the same, just like the winds that blow across the sand to create ripples. However, an international team of scientists has discovered an amazing mathematical feature of the megaripple: the ratio of the diameter of the largest particles to the diameter of the smallest is always constant.

Specimens have been studied from megaripple fields in Israel, China, Namibia, India, Jordan, Antarctica, and New Mexico in the United States. Further analysis was supplemented by observations made on Mars and the results of an experiment in a laboratory wind tunnel. "An extensive collection of terrestrial and extraterrestrial data, covering a wide range of geographic sources and environmental conditions, confirms the accuracy and reliability of this unexpected theoretical discovery," the researchers write.

The authors of the study conclude that in the future, this number can be used to classify different types of waves and what processes formed them.

The calculations can also be used to study past weather and climate patterns based on the sediments left behind by previous megaripples.

The results are even applicable beyond Earth: they could give us a better understanding of how megaripples are created on planets like Mars and what atmospheric conditions are needed for them to form, rather than other types of sand waves.

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