The artificial tooth kills bacteria. Free Technical Library News

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Artificial tooth kills bacteria

26.10.2015

Andreas Hermann of the University of Groningen in the Netherlands and colleagues have developed an antimicrobial plastic that can be used to print teeth that kill bacteria.

Scientists have incorporated antimicrobial ammonium salts into existing dental polymers. Such salts are positively charged and they destroy negatively charged bacterial membranes, causing them to burst and die. "This material can kill bacteria on contact, but on the other hand it is completely harmless to human cells," says Hermann.

The developers then put this mixture into a 3D printer, hardened it with ultraviolet light, and printed a range of dental objects like dentures and orthodontic braces. To test their antimicrobial abilities, the researchers applied a mixture of saliva and Streptococcus mutans, a bacterium that causes tooth decay, to the material. It turned out that the material killed 99% of the bacteria, especially when compared to the control sample without the addition of ammonium salts, where less than 1% of the microbes died.

Additional tests are needed before the development can be applied to patients, as the prostheses were kept in the salivary mixture for only six days. For clinical studies, this period should be significantly increased, as well as to test how new prostheses will interact with toothpaste.

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