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Program for the construction of synthetic DNA

05.10.2013

Programmers use off-the-shelf platforms like Python or Java to write code. By analogy with this, in the near future chemists will be able to use a set of algorithms to "write a program" that describes how a DNA molecule will behave in a test tube or cell.

A team of researchers from Washington (USA) has developed a programming language for chemists that will allow you to create a network to control chemical reactions. In medicine, such networks can serve as "smart" drug delivery or disease detectors at the cellular level.

Chemists now use chemical reaction equations to describe the "behavior" of a mixture of chemicals. Engineers at the University of Washington used the same language of equations, but went much further and created a program that controls the movement of molecules with given characteristics.

The researchers started from abstract mathematical descriptions of a chemical system and then used DNA to create molecules, which led to the desired result. Sooner or later, scientists hope, this technology can become a universal tool for building chemical reactions.

At present, the construction of molecular networks is a complex and cumbersome process that is almost impossible to reuse to create other systems. But the engineers are determined to create a basic structure that will give scientists more room for variation. This can be compared with programming languages, when the computer is given commands on what to do and why. Scientists draw parallels between humans and computers, reminding us that humans are a complex network of nanoscale molecules that are configured to work in a certain way. Today, scientists are looking for ways to develop synthetic systems that behave like biological systems, and hope that synthetic molecules can support the body's natural functions.

That is why it is necessary to create a system for the production of synthetic DNA molecules, the structure of which varies depending on the functions. And although the new approach is not yet ready for use in the medical field, in the future it will create molecules that will begin to self-assemble in cells and serve as "smart" sensors. They can be implanted into cells and programmed to detect anomalies and correct problems.

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Manufacturers of the Automatic Link device connected to the ODB-II connector, which up to this point worked as an on-board "recorder" with the function of displaying technological information on the smartphone screen, have now decided to turn it into a mobile wallet using Apple iBeacon technology.

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Now the device is available in the online store of the American company for $100. The gadget requires an application that can be downloaded from the App Store. An Android version is expected in the future.

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