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Generic Flu Cure

12.06.2012

An international team of scientists have published the results of their research into a universal flu cure in Nature Biotechnology.

Scientists have discovered a protein that could help fight a potentially deadly flu epidemic. Antiviral drugs made on the basis of this protein are able to "turn off" the main functions of the virus and prevent the serious consequences of infection. Through experiments in the lab, the new treatment proved effective and was able to block many strains of pandemic flu, including several H1N1 (Spanish flu, swine flu) and H5N1 (bird flu).

In their previous research, the scientists have used computer-aided design to create proteins that can target the vulnerable spots of the virus, with which it adapts to its environment. Now scientists have been able to optimize the design of proteins using deep DNA sequencing technology and eventually create a drug that effectively attacks the target structures of the virus. The technology used by the scientists allows simultaneously "sorting out" millions of variants of the protein structure, identifying and saving beneficial mutations. In this way, proteins can be reprogrammed, for example, to "connect" to the key structures of the virus and block them.

This study opens up the broadest possibilities for creating a universal cure for influenza. In addition, this technology can be applied to the development of drugs for many different infections.

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Random news from the Archive

Coffee Mysteries 05.02.2004

The caffeine found in coffee, tea, kola nut, and chocolate is generally thought to raise blood pressure.

Hypertensive patients are allowed only decaffeinated coffee. However, a study conducted at the University of Zurich (Switzerland) showed that in reality everything is much more complicated.

Fifteen healthy volunteers drank three cups of coffee each, receiving 250 milligrams of caffeine. For those who rarely drink coffee, systolic pressure increased by an average of 12,6 millimeters of mercury after an hour. And those who regularly consume this drink, the pressure remained unchanged. But what is most interesting: the participants of the experiment, who were unaccustomed to coffee, who received three cups of decaffeinated coffee, also increased their blood pressure - by 12 millimeters.

Moreover, when caffeine-accustomed subjects were injected with the substance directly into their bloodstream, their blood pressure rose as well. The only conclusion reached by the experimenters is that coffee contains many other substances that strongly influence the effect of caffeine.

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