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Light in rolls

07.11.2006

A new light source, a flexible luminous film, has been invented at the Munich Institute for Problems of Reliability and Microintegration (Germany).

In fact, it is a flat LED made of organic polymers that glows when an electrical voltage is applied. As is typical for LEDs, the luminous film consumes little energy and almost does not heat up. The brightness of the glow is smoothly adjustable. Longer life than incandescent or fluorescent lamps.

The original lighting device allows you to make the walls or ceiling of the room luminous. The novelty will find application in outdoor advertising, as well as in computer and cell phone screens.

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DNA electronic signature 18.10.2016

A device has been created that can sort single DNA molecules depending on their structure.

Traditional manipulations with DNA took place in a liquid medium: copying molecules, separating a mixture of molecules along the length using electrophoresis, sequencing. Then came what are called "new generation methods", they allow you to work with single molecules, and it is no longer necessary to prepare solutions.

Passing through a nanoporous electrically conductive membrane, a DNA molecule generates electric current fluctuations. They were called "squiggles", which can be translated as "scribbles" - seemingly random lines on a graph of current changes over time. However, they are not random: each nucleotide sequence has its own squiggles. Until recently, this phenomenon was a kind of exotic, the subject of discussions of theorists, but now the specialists of the company "Oxford Nanopore Technologies" have embodied it in a real portable device for "dry" sequencing called MinION. Software for reading the sequence has already been created, and the device itself flew to the ISS, where it was tested for its performance in microgravity conditions.

Researchers from the University of Nottingham, led by Dr. Matthew Luz, have created a signature library that contains many interesting DNA sections for the researcher - this allows you to recognize a molecule faster than it passes through a pore. By consulting the library, DNA molecules can be sorted, rejected, sequencing can be stopped after the desired nucleotide sequence is found - for example, the presence of a pathogenic microbe in the sample is confirmed. Dr. Luz hopes the method will find a variety of applications, including being used to accurately read parts of the human genome that are of interest to a doctor or scientist.

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