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Climate change could cause permanent allergies

21.10.2022

Experts from the Italian Society of Allergology, Asthma and Clinical Immunology (SIAAIC) warn that global warming may lead to the progression of hay fever, which now lasts one to two months.

According to experts, climate change will lead to a 200% increase in pollen produced by plants within a few decades. This causes severe and prolonged allergy symptoms.

The increase in temperature, allergists explain, determines the distribution of pollen of different types, which usually bloom in spring and summer, even in autumn. According to a study published in the journal Nature Communications, the critical season for allergies will start up to 40 days earlier in the spring and will be extended by three weeks in the fall.

"Already now we are fixing not only in the spring the complaints of allergy patients. And the warming will lead to the fact that many of them will suffer from pollinosis almost all year round," said Gianenrico Senna, president of SIAAIC, professor of respiratory diseases at the University of Verona (Italy), reports the news agency. ANSA.

The monitoring of airborne pollen in the atmosphere over the past 30 years already shows obvious changes. Scientists note that the extension of the pollination season in ragweed and parietaria, which now bloom from July to October.

"If we do not decide to drastically reduce CO2 emissions into the atmosphere, we will soon see an increase in pollen from plants. This will affect not only the duration of the allergy, but also its intensity," the expert warns.

The scientist advises the wise use of antihistamines. And although they have no contraindications, it is still important that they be prescribed by a specialist who can evaluate the possibility of specific allergen immunotherapy.

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Sunburn without UV 25.06.2017

A tan appears because ultraviolet stimulates the synthesis of melanin, a dark-colored pigment that must absorb ultraviolet radiation, preventing it from penetrating deeper and harming the deeper layers of the skin. But the skin will still receive some harm: the DNA in the cells will be damaged, and it remains only to hope for molecular repair enzymes that will correct these damages and prevent cell death or, even worse, the transformation of cells into cancerous ones.

However, life is simply not sweet for many without a tan, and they still go out into the sun again and again or go to the solarium. Is it possible to get tanned skin without being exposed to dangerous ultraviolet radiation? Researchers at the Massachusetts General Hospital and the Dana and Farber Cancer Institute say it is possible.

A few years ago, experts experimented with mice that were unable to synthesize melanin - such animals had a mutation in the genome that turned off pigment synthesis. But at the same time, it was found that a substance called forskolin could trigger the synthesis of melanin, bypassing the mutation, so that there was enough melanin to protect mice from the unpleasant effects of ultraviolet radiation.

However, at the same time it turned out that forskolin is useless for humans: compared to mice, our skin is thicker, and the substance simply does not penetrate to a sufficient depth. However, the researchers were able to find another compound - more specifically, a whole class of compounds that are similar in action to forskolin and that are effective on human skin. Cells have special enzymes, abbreviated as SIK, on ​​which the activity of genes that control melanin synthesis depends. Scientists have studied molecules that inhibit the activity of SIK proteins, thereby activating pigment synthesis. The specific molecular mechanism is different than with forskolin, but the end result is the same: a UV-free tan.

Before any drugs with "tanning molecules" appear on the market, you need to make sure that they will not have any oncological and generally any harmful effects.

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