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Potato bacterium antibiotic

13.10.2022

British scientists have managed to obtain a broad-spectrum antibiotic from a potato bacterium.

We are talking about a microorganism called Dickeya solani, first discovered 15 years ago. It is he who is responsible for the so-called wet rot on potatoes, which everyone has seen. This disease harms agriculture, but helped scientists from the University of Cambridge (UK) discover a new broad-spectrum antibiotic.

Previously, microbiologists have already found that the bacterium D. solani has the ability to secrete an antibiotic, but another one is oocidin A. It has a high activity against many fungal infections in plants.

It turned out that the bacterium can secrete another antibiotic - solanimicin. Scientists got it when they inhibited the genes responsible for the production of oocin A. Despite this inhibition, D. solani continued to retain antifungal activity.

The researchers asked why this was so and learned about the bacterium's "backup" defense. In addition to isolating the antibiotic itself, the authors of the work identified a cluster of genes encoding the proteins that make up the compound.

Scientists have also found that the microorganism spends this type of antibiotic sparingly - for example, solanimycin genes are activated by an acidic environment. In the future, biologists hope to extract from it a drug that would be effective in protecting plants, and in the future, people from pathogens.

In the laboratory, researchers have already tested the antibiotic against Candida albicans and it is effective. This type of fungus exists naturally in the body, but it can also trigger dangerous infections.

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Elephants on a treadmill 14.07.2003

Can elephants run, or do they simply walk at a fast pace if necessary? A group of Thai biologists studied the issue by running 42 Asian elephants on a treadmill.

A total of 188 races were held under the lens of television cameras. To make it possible to analyze the movements of the legs of thick-skinned giants on video frames, the joints were marked on the elephant skin with spots of white paint. The speed was recorded with a photo finish.

It turned out that elephants use something between fast walking and running. The order and mode of movement of the legs does not change, and there are no moments when all four legs leave the ground, as in typical running of other animals. On the other hand, when the elephant moves to a fast pace, the body's center of gravity begins to jump up and down, which is typical for running (when walking, the elephant's center of gravity shifts back and forth).

Many of the experimental animals reached speeds of 25 kilometers per hour, and three particularly nimble individuals exceeded it. This is the first time that such speeds have been recorded in elephants. The conclusion of zoologists: with some stretch, we can assume that elephants can run.

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