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Ultrasound makes the band-aid more sticky

21.08.2022

Researchers have found that they can control the stickiness of medical adhesives using ultrasonic waves and bubbles. The development will allow the patch to be applied, for example, to wet skin, according to McGill University (Canada).

To make the adhesive stickier, the team experimented with the intensity of the ultrasound to create microbubbles in the adhesive.

Ultrasound induces many microbubbles that push the adhesive against the skin for a stronger bioadhesion momentarily. With this method, scientists can, for example, precisely control the stickiness of medical patches or adhesive dressings on many tissues.

The study shows that bioglue is compatible with living tissues of rats. It can also potentially be used to deliver drugs through the skin.

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Gene rejuvenation 30.04.2016

Elizabeth Parrish, CEO of US research company BioViva, has become the first person to successfully test anti-aging gene therapy.

Despite the fact that we notice the first age-related changes by external signs, aging processes are formed and develop inside - at the cellular level. The ends of chromosomes are called telomeres. They do not carry genetic information, but protect the chromosomes, acting as a kind of "buffer" against wear and tear. However, each time a cell divides, the telomeres gradually decrease until they are so short that they can no longer protect the chromosomes. As a result, the cell ages and can no longer perform its functions.

An enzyme called telomerase is able to complete short telomeres. Aging body cells, thanks to telomerase, again acquire the ability to divide, like young and healthy cells. So far, the telomere lengthening technique has only been tested in cultured cells and laboratory animals.

The first experiment to test a unique rejuvenation technique on a person started in September 2015, when 44-year-old Elizabeth decided to undergo two experimental gene therapy courses developed by her employees to slow down aging. The first course is designed to prevent loss of muscle mass with age, and the second is aimed at increasing the production of telomerase. The injections were given to Elizabeth in Colombia as the drugs are not approved by the US Food and Drug Administration (FDA).

Now the first results of gene therapy have become known - and they are stunning! The analyzes showed that the drugs actually stopped the shortening of telomeres. Leukocytes in Parrish's blood became biologically younger, and telomeres "lengthened" by 20 years. The discovery of BioViva has attracted the attention of both scientists and investors, while the experiment continues and the researchers carefully monitor Parrish's health.

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