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bacterium noise

28.04.2022

The team of scientist Farbod Alijani at the Delft University of Technology captured the noise that bacteria make while initially investigating the underlying physical mechanics of graphene.

Graphene is a form of carbon made up of a single layer of atoms, also known as the wonder material.

It is very durable, with good electrical and mechanical properties, and is also extremely sensitive to external forces. This animation shows how a graphene drum can make bacteria sounds. The sound stops when the bacteria is killed by the antibiotic.

When a single bacterium sticks to the surface of a graphene drum, it generates random vibrations with an amplitude of only a few nanometers that could be detected.

Scientists were able to hear the sound of a single bacterium! To understand how tiny these blows of the flagellum on graphene are, it is worth saying that they are at least 10 billion times smaller than the blow of a boxer when he reaches a punching bag. However, these nano-sized bits can be converted into audio tracks and listened to - and how cool it is.

Scientists say that this study is of great importance in identifying resistance to antibiotics. At the same time, the results of the experiment were unambiguous: if the bacteria were resistant to the antibiotic, the fluctuations simply continued at the same level. When the bacteria were susceptible to the drug, the fluctuations decreased to one or two hours, but then they completely disappeared. Due to the high sensitivity of graphene drums, this phenomenon can be detected using just one cell.

“In the future, we aim to optimize our single-cell graphene antibiotic susceptibility platform and test it on a variety of pathogenic samples, so that it can eventually be used as an effective diagnostic tool to quickly detect antibiotic resistance in clinical practice,” the scientists noted.

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