Antimicrobial coating for orthopedic implants. Free Technical Library News

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Antimicrobial Coating for Orthopedic Implants

30.09.2021

Scientists from Los Angeles have presented a mixture that can be applied to orthopedic implants a few minutes before surgery, which eliminates the possibility of infection of the implant.

In early trials in mice, the coating prevented all subsequent infections, even without the introduction of antibiotics into the bloodstream. After 20 days, the coating did not reduce the ability of the bone to fuse with the implant and was completely absorbed by the body.

The new antimicrobial coating consists of two polymers, one that repels water and the other that mixes well with water. Both drugs are mixed in solution with an antibiotic. When exposed to bright ultraviolet light, the two polymers fuse. Tests with various types of implants have shown that the coating is very difficult to remove during surgical interventions. However, once ingested, the conditions cause the polymer to degrade, slowly releasing the antibiotics over a period of two to three weeks.

The invention is very important for people with cancer and weakened immune systems, who are very susceptible to infection.

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