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Chemotherapy improvement

12.09.2021

The use of low-intensity pulsed ultrasound in combination with microbubbles can improve the delivery of chemotherapy drugs used to treat cancer. In their study, a group of Lithuanian researchers from three universities reported that the survival time of microbubbles is the best indicator for determining the effectiveness of sonoporation, that is, the rupture of the cancer cell membrane caused by ultrasound.

To date, a method in which ultrasound, along with microbubbles, is used to improve the delivery of anti-cancer drugs to affected cells is being widely studied. Although most of the research is carried out in vitro laboratory conditions, the first clinical trials have already begun. A new class of anti-cancer drugs could be effective in treating common types of leukemia.

"Our main finding is that only an estimate of the microbubble survival time is needed to predict the effectiveness of sonoporation. Therefore, our metrics are more advanced than the currently used inertial cavitation control variable," the study authors explain.

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Over the past few years, scientists have been closely studying the behavior of skyrmions and reasonably believe that these structures will help to significantly increase the magnetic recording density. Moreover, recently British and American scientists have found a way to increase the recording density by several times using skyrmions without special difficulties in the form of reducing the diameter of vortex structures, which can lead to the speedy translation of scientific thought into a commercial product.

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Scientists from England presented the creation of the structure of the "bag of skyrmions" in the form of an abstract model and reproduced the phenomenon in a simulator program. Their American colleagues reproduced the phenomenon in practice, although they used liquid crystals rather than magnetic structures to launch vortex structures. Liquid crystals are known to be controlled by a magnetic field, which allows them to be used for staged experiments to visualize magnetic phenomena. We are waiting for the transfer of experiments to magnetic films.

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