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Growing new teeth

10.04.2021

Japanese researchers have developed an experimental technique for growing teeth. Now this technology is being tested on laboratory animals. The method of treatment with monoclonal antibodies is described. These antibodies cause the body to grow new teeth.

As part of the study, it was possible to fix that blocking a gene called USAG-1 leads to an increase in the activity of bone morphogenetic protein. These molecules regulate the growth of various organs and tissues, including teeth.

However, this technology has several nuances. The fact is that the morphogenetic protein controls the development of a huge number of human organs. Interference with its work can cause many serious side effects.

During the experiments, the team tested a number of different monoclonal antibodies that alter the ability of USAG-1 to interact with bone morphogenetic protein. Fortunately, the researchers found a specific antibody that didn't cause side effects.

After that, the method was tested on animals. In this way, the team was able to stimulate tooth growth in laboratory mice. Subsequent experiments on ferrets yielded successful results.

Interestingly, ferret teeth are more like human teeth. Therefore, the success of research on these animals gives hope that the results of experiments with humans will also justify themselves.

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Soft electronics has become multi-layered 22.08.2018

Soft PCBs could change the way we think about electronic devices. Flexible and soft electronics will allow you to create medical sensors that you can comfortably wear on yourself without fear of breaking. But how soon will we have such devices?

Various research groups have repeatedly demonstrated prototypes of soft electronics. As a rule, in such cases, they try to combine existing electronic components with a soft and durable substrate, or they try to create new flexible transistors and microcircuits. The employees of the University of California at San Diego have taken another step towards the release of "electronic-soft" technologies beyond the walls of laboratories. They took the first path by incorporating microscopic components into elastomer substrates, a polymer with high elasticity and viscosity.

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In the future, the California laboratory intends to further increase the number of layers. Perhaps thanks to this technology, amazing new medical devices and all kinds of agile and agile soft robots will appear faster than we think.

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